Aims: Divided nevus of the eyelid is a congenital pigmented nevus that impacts eyelid function and aesthetics. While surgical excision and laser ablation are current treatment options, they have limitations when dealing with large lesions. This study aims to investigate the efficacy and safety of carbon dioxide (CO₂) laser excision treatment for divided nevus of the eyelid. Methods: This retrospective study included 10 patients (5 males, 5 females) with a mean age of 23.7 years (9-54 years). All underwent CO₂ laser excision and were followed up for 12 months. Treatment outcomes were assessed through clearance and recurrence rates, evaluated using digital photography. Postoperative complications were closely monitored throughout the 12-month follow-up period. Patient satisfaction was assessed using a comprehensive questionnaire. Results: All patients presented with unilateral divided nevus of the eyelid, with lesion diameters ranging from 25 to 50 mm and heights ranging from 0.3 to 6 mm (mean: 3.93 mm). Patients received between 1 and 5 laser treatment sessions. At the 12-month follow-up, a 100% clearance rate was achieved, with no recurrence observed in any patient. All patients maintained a continuous eyelid margin with acceptable irregularity. Complications were minimal, with partial eyelash loss in 8 patients, hyperpigmentation in 2 patients, and mild upper eyelid trichiasis in 1 patient. No severe complications, such as ectropion, eyelid margin notching, corneal erosion, or significant scar hypertrophy, were reported. All patients expressed being "very satisfied" with the functional and cosmetic outcomes in a questionnaire. Conclusions: CO₂ laser excision offers a simple, precise, and effective treatment approach for divided nevus of the eyelid. This innovative technique simplifies the treatment process, achieves excellent cosmetic outcomes, and eliminates the need for skin grafting, making it a promising option for the management of large divided nevus.

Aims: This study aims to investigate the efficacy and safety of carbon dioxide (CO?) laser treatment for divided nevus of the eyelid. Methods: This retrospective study included 10 patients (5 males, 5 females) with a mean age of 23.7 years (9-54 years). All underwent ultrapulse CO? laser excision and were followed up for 12 months. Treatment outcomes were assessed through clearance rates and recurrence, evaluated using digital photography. Complications and patients’ satisfaction were also assessed. Results: All patients presented with unilateral divided nevus of the eyelid, with lesion diameters ranging from 25 to 50 mm and heights ranging from 0.3 to 6 mm (mean: 3.93 mm). At the 12-month follow-up, the clearance rate was 100%, with no recurrence observed. Postoperative complications were minimal, with partial eyelash loss, hyperpigmentation, and only one case of mild upper eyelid trichiasis. Patients reported high satisfaction with both functional and cosmetic outcomes. Conclusion: CO? laser excision offers a simple, precise, and effective treatment approach for divided nevus of the eyelid. This modality simplifies the treatment process, achieves excellent cosmetic outcomes, and eliminates the need for skin grafting, making it a promising option for the management of large divided nevus.

Aims: To analyze the characteristics and trends of non-tumor-related eye removal in Southern China from 2009 to 2018. Methods: Inpatient data from Zhongshan Ophthalmic Center were examined to identify trends and characteristics of non-tumorous enucleation/evisceration. The Chi-square test assessed differences in age, gender, and etiology, while linear regression analyzed the significance of trends from 2009 to 2018 across subgroups. The nonquadratic Mann-Kendall test evaluated the trends in etiology and types of ocular injuries. Results: A total of 1824 patients (mean age 28 years, SD 19.2) underwent non-tumor-related eye removal during the study period. The majority were male (73.1%), with ocular trauma (72.3%) and corneal perforation (7.7%) being the leading causes. Work-related injuries accounted for 30.5% of ocular trauma, showing a moderate increase over the decade. However, no statistically significant trends were observed in the etiology or specific causes of ocular trauma. Conclusions: The rates of non-tumorous eye removal remained stable from 2009 to 2018. Ocular trauma was the predominant non-tumorous cause of enucleation or evisceration in Southern China. Translational Relevance: The findings highlight the need for preventive measures against work-related injuries leading to enucleation and the importance of rigorous childcare to mitigate the risk of eye removal due to trauma.

Background: To measure the anterior and posterior segment structural features of acute primary angle-closure (APAC) eyes.

Methods: A total of 36 subjects with unilateral APAC were recruited in this study. The ocular biometric characteristics were measured by anterior segment optical coherence tomography (AS-OCT) and swept source optical coherence tomography (SS-OCT), respectively at baseline, 2 weeks, and 1 month after surgical intervention.

Results: At baseline, when compared with the fellow eyes, APAC-affected eyes showed significantly greater corneal thickness (P=0.004), shallower anterior chamber depth (ACD) (P<0.001), smaller anterior chamber area (ACA) (P=0.013), angle opening distance at 750 μm from the scleral spur (AOD750) (P=0.002), trabecular–iris space area at 750 μm from the scleral spur (TISA750) (P=0.033), angle recess area (ARA) (P=0.014), and iris area (IARE) (P=0.003), less iris curvature (ICURVE) (P=0.003), and larger lens vault (LV) (P=0.030). After intervention, the corneal thickness was significantly decreased at 1 month (P<0.001), while ACD, ACA, and AOD750 were significantly increased at 2 weeks and 1 month (all P<0.017). Changes in ACD were correlated with decreasing LV (P<0.05). The posterior segment parameters did not change over the 4-week period.

Conclusions: When compared with the fellow eyes, APAC-affected eyes had greater corneal thickness, shallower anterior chamber, narrower angle, less ICURVE, and larger LV. After intervention, the corneal thickness was decreased, while the shallower anterior chamber was relieved to some extent.