Purpose: To investigate clinical efficacy and continuity of care measures for foldable capsular vitreous body (FCVB) implantation and to evaluate its nursing effect and adverse complications. Methods. Retrospective analysis. The test group consisted of 75 eyes of 75 patients who underwent FCVB implantation for severe ocular trauma, complex retinal detachment and silicone oil-dependent eyes between August 2017 and April 2022 in our hospital. The control group consisted of 80 eyes of 80 patients who underwent vitrectomy and silicone oil filling for vitreous hemorrhage and retinal detachment at the same period. All patients were treated with a continuity of care model, and the postoperative Best-corrected visual acuity changes, intraocular pressure (IOP), retinal reset rate, adverse complications and regression, number of follow-up visits, and patient satisfaction were compared between the two groups. Results: No changes were presented on BCVA after treatment in test group. The percentage of BCVA improvement was greater in the control group compared with the test group (P < 0.05). No changes were presented on IOP after treatment in both groups. The postoperative IOP in the control group was significantly higher than that in the test group (P < 0.001). The retinal reset rate, incidence of low IOP, incidence of anterior chamber hemorrhage, incidence of corneal degeneration, proportion of anterior chamber inflammatory cell grade ≥2, number of sympathetic ophthalmia, and the average number of follow-up visits in the test group were significantly higher than those in the control group, while the incidence of high IOP and vitreous hemorrhage were significantly lower than those in the control group 3 months after treatment. Corneal degeneration was classified as not cured, low IOP and sympathetic ophthalmia were classified as improved, and the rest of the adverse complications were classified as cured. The average number of follow-up visits in the test group was significantly higher than that in the control group (P < 0.05), and patient satisfaction in the test group was higher than that in the control group, but there was no significantly statistical difference (P > 0.05). Conclusion: The FCVB is a safe, feasible, and effective vitreous substitute. Strengthening the nursing measures of FCVB implantation, emphasizing person-centred care and continuity of care, and improving surgical efficacy and patient satisfaction.
Purpose: To investigate clinical efficacy and continuity of care measures for foldable capsular vitreous body (FCVB) implantation and to evaluate its nursing effect and adverse complications. Methods. Retrospective analysis. The test group consisted of 75 eyes of 75 patients who underwent FCVB implantation for severe ocular trauma, complex retinal detachment and silicone oil-dependent eyes between August 2017 and April 2022 in our hospital. The control group consisted of 80 eyes of 80 patients who underwent vitrectomy and silicone oil filling for vitreous hemorrhage and retinal detachment at the same period. All patients were treated with a continuity of care model, and the postoperative Best-corrected visual acuity changes, intraocular pressure (IOP), retinal reset rate, adverse complications and regression, number of follow-up visits, and patient satisfaction were compared between the two groups. Results: No changes were presented on BCVA after treatment in test group. The percentage of BCVA improvement was greater in the control group compared with the test group (P < 0.05). No changes were presented on IOP after treatment in both groups. The postoperative IOP in the control group was significantly higher than that in the test group (P < 0.001). The retinal reset rate, incidence of low IOP, incidence of anterior chamber hemorrhage, incidence of corneal degeneration, proportion of anterior chamber inflammatory cell grade ≥2, number of sympathetic ophthalmia, and the average number of follow-up visits in the test group were significantly higher than those in the control group, while the incidence of high IOP and vitreous hemorrhage were significantly lower than those in the control group 3 months after treatment. Corneal degeneration was classified as not cured, low IOP and sympathetic ophthalmia were classified as improved, and the rest of the adverse complications were classified as cured. The average number of follow-up visits in the test group was significantly higher than that in the control group (P < 0.05), and patient satisfaction in the test group was higher than that in the control group, but there was no significantly statistical difference (P > 0.05). Conclusion: The FCVB is a safe, feasible, and effective vitreous substitute. Strengthening the nursing measures of FCVB implantation, emphasizing person-centred care and continuity of care, and improving surgical efficacy and patient satisfaction.
Dry eye is a group of eye diseases characterized by complex and diverse symptoms. Symptoms are one of the diagnostic criteria for dry eye and are closely related to health outcomes such as quality of life of patients. Relieving symptoms is the primary goal of dry eye treatment and management. Patient self-reported outcome is the gold standard for symptom assessment. This paper reviews the self-reported outcome assessment tools for patients with dry eyes at home and abroad, analyzes and compares their contents, usage status, reliability and validity, advantages and disadvantages, hoping to provide theoretical basis for medical staff to choose assessment tools for dry eye symptom management.
Objective: To investigate the effect of anterior and posterior capsule polishing on reducing the occurrence of posterior capsule opacities (PCO) in cataract phacoemulsification surgery. Method: 92 patients (104 eyes) with age-related cataracts, aged 55-78 years, with a grading of II-IV for lens opacity, underwent I/A anterior capsule peripheral polishing and flushing spherical frosted polishing of the posterior capsule during phacoemulsification with a 2.4mm micro incision at the steep axis of the corneal margin. Clinical observations were conducted on intraoperative and postoperative complications, postoperative visual acuity, and posterior capsule condition. 96 patients (106 eyes) who underwent phacoemulsification with a 2.4mm micro incision at the steep axis of the corneal margin during the same period were selected as the control group, with a grading of II-IV for lens opacity. Result: The incidence of cystic opacity at 1 month, 3 months, 6 months, 1 year, and 2 years after surgery was 0.96% (1/104), 0.96% (1/104), 1.92% (2/104), 2.88% (3/104), and 5.77% (6/104), respectively. There was a significant difference compared to cases without cystic membrane polishing during the same period. Conclusion: After statistical analysis, the incidence of postoperative complications in patients who underwent anterior and posterior capsule polishing during surgery was significantly lower than that in patients who did not undergo capsule polishing (P<0.05).
Objective: To evaluate early visual quality between topography-guided femtosecond laser-assisted laser in situ keratomileusis（FS-LASIK）and small incision lenticule extraction (SMILE) in treating moderate myopia and astigmatism. Methods: Retrospective comparative was performed. 52 patients (52 eyes) with myopia and astigmatism who wanted refractive surgery were selected in Yantai Aier Hospital from June 2022 to January 2023. The patients were allocated to either one of two groups according to each person's request. The topography-guided FS-LASIK (TOPO-G) group had 26 patients (26 eyes) and the SMILE group had 26 patients (26 eyes). All patients were followed up for 3 months. Uncorrected visual acuity (UCVA) was measured 1 day, 1 week, 1 month and 3 months after surgery. Spherical equivalent (SE) and cylinder diopter were measured 1 week, 1month and 3 months after surgery. Corneal higher-order aberration (HOA) including total HOA, spherical aberration, coma, trefoil and modulation transfer function (MTF) were measured by i-Trace visual function analyzer at 3 months after surgery. Independent t-test was used for inter-group comparison, while repeated measures ANOVA was used to analyze changes at different time points. Results: In both groups, 100% of the eyes obtained a UCVA of 20/20 or better at 1week, 1 month and 3 months postoperatively (P＞0.05), but there were no significant differences between the two groups. At 1wk postoperatively, SE was higher in the TOPO-G group than in SMILE group (t=3.088, P=0.003). At 3mo postoperatively, the SE reached target refraction in both groups(P＞0.05). The residual astigmatism was reduced between the two groups without intergroup difference after surgery (P＞0.05). HOAs under 5 mm pupil size were reduced than preoperative levels in both groups at 3mo postoperatively (P<0.05). The MTFs were significantly higher in the TOPO-G group than in the SMILE group at 5, 25, 30 spatial frequencies at 3mo postoperatively (P<0.05). Conclusions: The topography-guided FS-LASIK and SMILE are both effective methods to correct ametropia. Early postoperative improvement in MTF at high spatial frequency were better after the topography-guided FS-LASIK than SMILE.
Glaucoma is the world's first irreversible blinding eye disease, characterized by degenerative changes in retinal ganglion cells (RGC), which have a significant impact on the global economy and health. The molecular and biological mechanisms of its pathological changes are still unclear. At present, glaucoma surgery and drug therapy are still limited to controlling the intraocular pressure in the normal range. Three-dimensional culture technology can enable cells to form a certain spatial structure in vitro, which is conducive to cell-cell and cell-environment interactions. Compared with traditional two-dimensional culture, three-dimensional culture technology is closer to the physiological environment of cells in vivo, which is of great significance for the study of pathophysiological changes of diseases and high-throughput drug screening. This review discusses the application of trabecular mesh and three-dimensional culture of retinal cells in the basic research of glaucoma, aiming to provide new ideas for further exploring the pathophysiological mechanism of glaucoma.
Chronic Liver Disease (CLD) is a collective term for diseases resulting from the long-term effects of one or more damaging factors on the liver. It has a broad impact and affects a large patient population. Viral hepatitis, non-alcoholic fatty liver disease, and end-stage liver disease can involve the ocular fundus, leading to retinal exudates and hemorrhages. Additionally, structural changes in the fundus, such as the thickness of the choroid and different retinal layers, are associated with the severity of chronic liver disease. Through fundus examinations in patients with chronic liver disease, not only can ocular complications related to liver disease be prevented and treated, but these examinations may also offer potential value in the clinical assessment and monitoring of liver disease. This article reviews the potential ocular fundus abnormalities in patients with chronic liver disease under different etiologies, severities, and drug treatments. It discusses the progress in the clinical application of fundus structure and function examinations in patients with chronic liver disease. It compares the characteristics and appropriate clinical scenarios of various fundus examination methods in these patients and suggests potential new directions for the future use of fundus examinations in chronic liver disease management.
Myopia is recognized as one of the most pressing global public health challenges, particularly in East Asia. The rising prevalence of myopia imposes a considerable socioeconomic burden, with high myopia being associated with an increased risk of irreversible vision loss. Contemporary lifestyle changes have led to significant alterations in light exposure patterns, which may play a crucial role in the onset and progression of myopia. Investigating how ametropia is influenced by various light conditions could provide valuable insights for developing effective myopia prevention strategies. In this review, we aim to elucidate the current understanding of the relationship between myopia and light exposure, examine potential light-mediated molecular and physiological mechanisms, and explore management strategies for myopia.
Glaucoma is a group of optic nerve degenerative diseases characterized by papillary atrophy, visual field defects, and decreased vision. It is also the leading cause of irreversible blindness worldwide, which reduces the quality of life of patients and causes significant health economic burdens. However, the pathogenesis of glaucoma is still unclear, and promoting aqueous humor outflow to reduce intraocular pressure remains the only treatment option to slow disease progression. The main pathway for aqueous humor outflow is through the trabecular meshwork into Schlemm's canal and finally into the episcleral veins, indicating that the trabecular meshwork plays a vital role in regulating aqueous humor outflow and balancing intraocular pressure. In recent years, there have been breakthroughs in in vivo and in vitro aqueous humor outflow measurement techniques and trabecular meshwork imaging technologies, with many studies suggesting that the trabecular meshwork exhibits pressure-dependent rhythmic pulsation, playing a crucial role in the pulse-like outflow of aqueous humor. However, in glaucoma, this pulsation weakens or even disappears as the disease progresses. This article will focus on the trabecular meshwork's pump theory and summarize the latest research progress in aqueous humor outflow in glaucoma, exploring potential effective therapeutic strategies from restoring trabecular meshwork function to provide new ideas for the clinical diagnosis and treatment of glaucoma.
Age stands as a primary risk factor for diseases and disabilities among the elderly. To effectively assess the underlying aging processes, accurate measures of biological age and rates of aging across multiple levels of aging features are essential. Biological age, derived from physiological assessments of systems and organs, has emerged as a superior predictor of age-related diseases and mortality compared to chronological age. Recent advancements in machine learning have catalyzed the development of sophisticated models capable of quantitatively characterizing biological aging with different types of data. This review explores the machine learning models in advancing our understanding of biological aging, highlighting the potential of these innovative approaches to facilitate aging research and personalized healthcare strategies.
