目的：比较不同预设光学区组的飞秒激光小切口基质透镜取出术(small incision lenticule extraction，SMILE)和飞秒激光制瓣联合准分子激光原位角膜磨镶术(femtosecond laser-assisted in situ keratomileuses，FS-LASIK)术后有效光学区(effective optical zone，EOZ)大小与角膜高阶像差(high order aberrations，HOAs)变化以及有效光学区大小对角膜高阶像差的影响。方法：收集2019年2月 至2020年5月来佛山市第二人民医院行激光手术的患者80例，均取右眼入组，SMILE组43例，FSLASIK组37例，按预设光学区大小分为6.5 mm和6.0 mm组，分别于术前和术后1个月应用Pentacam三维眼前节分析系统测量有效光学区及总角膜高阶像差、彗差、球差，分析不同预设光学区下SMILE组和FS-LASIK组有效光学大小及与角膜高阶像差的关系。结果：在相同预设光学区下，术后1个月SMILE组的有效光学区均大于FS-LASIK组，差异均有统计学意义(均P<0.05)，且SMILE组的角膜总高阶像差、球差、彗差均较FS-LASIK组低，差异均有统计学意义(均P<0.05)；对于相同手术方式，预设光学区6.0 mm较6.5 mm组，术后1个月角膜总高阶像差、球差、彗差均升高，差异均有统计学意义(均P<0.05)。结论：SMILE组和FS-LASIK组术后1个月的有效光学区均小于预设光学区，SMILE组大于FS-LASIK组；术后1个月有效光学区越大，角膜高阶像差越小；在相同预设光学区下，SMILE组术后1个月角膜高阶像差小于FS-LASIK组。

Objective: To compare the effective optical zone (EOZ) and the changes in corneal high order aberrations (HOAs) after small incision lenticule extraction (SMILE) with those after femtosecond laser-assisted in situ keratomileuses (FS-LASIK). Methods: This study included 80 subjects who underwent laser refractive surgery at the Second People’s Hospital of Foshan between February 2019 and May 2020. Only data from the right eye of each subject were analyzed. A total of 43 eyes underwent SMILE while 37 eyes received FS-LASIK. The eyes were further stratified into subgroups based on different programmed optical zones: the 6.5 mm group and the 6.0 mm group. EOZ, coma, and spherical aberration were measured with Pentacam 3D anterior segment analysis system preoperatively and one month postoperatively. In addition, the relationship between EOZ and corneal HOAs was analyzed and compared between different optical-zone groups after SMILE and FS-LASIK. Results: For the same programmed optical zone, the SMILE group achieved a significantly greater EOZ than the FS-LASIK group who was measured 1-month postoperatively did (P<0.05). Meanwhile, corneal HOAs, spherical aberration, and coma in the SMILE group are significantly lower than those in the FS-LASIK group (P<0.05). For the same procedure (SMILE or FS-LASIK), the 6.0 mm group demonstrated significantly higher corneal total HOAs, spherical aberration, and coma than the 6.5 mm group did 1-month after the surgery (P<0.05). Conclusion: In both the SMILE and the FS-LASIK groups, 1-month postoperative EOZ was smaller than the programmed optical zone. EOZ in the SMILE group was larger than that in the FS-LASIK group. The larger the 1-month postoperative EOZ was, the lower corneal HOAs were. For the same programmed optical zone, 1-month postoperative corneal HOAs in the SMILE group is lower than that in the FS-LASIK group.

目的：像差和对比敏感度检查结果数据繁多复杂。为了高效准确地完成检查数据提取工作，自主开发一款像差和对比敏感度数据提取处理软件(Aberrations and Contrast Sensitivity Helper，ACSH)。方法：参考其他同类软件的设计模式，结合我院科研实际，采用开发工具VB6.0编程实现。结果：ACSH在Windows的运行环境下，能够准确地在局域网环境下实现对iTrace，Zywave像差仪和Optec_6500对比敏感度测试仪的检查数据进行提取。像差仪信息包括病人基本信息、屈光度、眼别、瞳孔直径，各项像差Zernike系数，高阶像差和总高阶像差均方根RMS(Root Mean Square)。对比敏感度仪数据包括：病人基本信息、检查时间、检查时的模拟光照度和眩光强度、 各空间频率的对比敏感度数值。同时软件支持对已提取的数据进行浏览、查询及导出EXCEL等功能，并开放数据接口供电子病历等其他系统对接。结论：ACSH是一款能够有效辅助视光专科科研和临床工作的应用软件。

Objective: Aberration and contrast sensitivity test results data is various and complex. In order to complete efficiently and accurately the data extraction work, we developed an aberration and contrast sensitivity data extraction software Aberrations and Contrast Sensitivity Helper (ACSH). Methods: VB6.0 was used as a development tool after we referred to other similar software design pattern and combined the reality of our scientific research. Results: The ACSH under the Windows environment can accurately extract the results’ data of iTrace and Zywave aberration meter and Optec 6500 contrast sensitivity tester in local area network. Aberration instrument information include patients’ basic information, refraction, which eye, pupil diameter, the aberration  Zernike coefficients, the high-order aberration and total aberration Root Mean Square (RMS). Contrast sensitivity tester data included: patients’ basic information, time, the intensity of analog light and the glare ,the contrast sensitivity values of every spatial frequency. ACSH is able to browse and query extracted data and export to EXCEL, and open data interface for electronic medical records and other system. Conclusion: ACSH is an effective software which assists optical specialized scientific research and clinical work.