目的：开发一款可自动校准测试距离的智能手机视力检测APP(WHOeye的iOS版本)，并评估其实用性。方法： WHOeyes在经过验证的视力检测APP “V@home”的基础上新增自动距离校准(automatic distance calibration, ADC)功能。研究招募了3组不同年龄(≤20岁、20~40岁、>40岁)的中国受试者，分别使用糖尿病视网膜病变早期治疗研究(Early Treatment Diabetic Retinopathy Study, ETDRS)视力表和WHOeyes进行远距离和近距离的视力检测。ADC功能用于确定WHOeyes的测试距离。红外测距仪用于确定ETDRS的测试距离以及WHOeyes的实际测试距离。通过问卷调查评估用户满意度。结果：WHOeyes ADC确定的实际测试距离在3个年龄组中均与预期测试距离总体上表现出良好的一致性(P > 0.50)。在远距离和近距离视力检测方面，WHOeyes的准确性与ETDRS相当。WHOeyes与ETDRS之间的平均视力差异范围为–0.084 ~ 0.012 log^MAR，各组的二次加权卡帕系数(quadratic weighted kappa, QWK)均大于0.75。WHOeyes在近距离和远距离视力检测中的重测信度高，平均差异范围为–0.040 ~ 0.004 log^MAR，QWK均大于0.85。问卷调查显示WHOeyes具有较好的用户体验和接受度。结论：与金标准ETDRS视力表方法相比，WHOeyes测试距离较为准确，可以提供准确的远距离和近距离视力测量结果。

Background: To develop and assess usability of a smartphone-based visual acuity (VA) test with an automatic distance calibration (ADC) function, the iOS version of WHOeyes. Methods: The WHOeyes was an upgraded version with a distinct feature of ADC of an existing validated VA testing APP called V@home. Three groups of Chinese participants with different ages (≤20, 20-40, >40 years) were recruited for distance and near VA testing using both an Early Treatment Diabetic Retinopathy Study (ETDRS) chart and the WHOeyes. The ADC function would determine the testing distance. Infrared rangefinder was used to determine the testing distance for the ETDRS, and actual testing distance for the WHOeyes. A questionnaire-based interview was administered to assess satisfaction. Results: The actual testing distance determined by the WHOeyes ADC showed an overall good agreement with the desired testing distance in all three age groups (p > 0.50). Regarding the distance and near VA testing, the accuracy of WHOeyes was equivalent to ETDRS. The mean difference between the WHOeyes and ETDRS ranged from -0.084 to 0.012 log^MAR, and the quadratic weighted kappa (QWK) values were greater than 0.75 across all groups. The test-retest reliability of WHOeyes was high for both near and distance VA, with a mean difference ranging from -0.040 to 0.004 log^MAR and QWK all greater than 0.85. The questionnaire revealed an excellent user experience and acceptance of WHOeyes. Conclusion: WHOeyes could provide accurate measurement of the testing distance as well as the distance and near VA when compared to the gold standard ETDRS chart.

1111

1111

图1为Marfan氏综合征之晶体半脱位的局部特写。散瞳状态下，裂隙灯斜照显示晶状体曲率增加，尤其是后曲率增加更加明显；又加之下方可见丝丝缕缕的悬韧带，细细观察竟能区分出双股分离(晶状体前后两组悬韧带的部分松弛和断裂)，整体望去犹如火焰助推下准备腾空的一枚热气球。此照片的价值在于，能在直视下观察到活体晶状体的前后两组悬韧带，兼具有想象空间的美感。

图1为Marfan氏综合征之晶体半脱位的局部特写。散瞳状态下，裂隙灯斜照显示晶状体曲率增加，尤其是后曲率增加更加明显；又加之下方可见丝丝缕缕的悬韧带，细细观察竟能区分出双股分离(晶状体前后两组悬韧带的部分松弛和断裂)，整体望去犹如火焰助推下准备腾空的一枚热气球。此照片的价值在于，能在直视下观察到活体晶状体的前后两组悬韧带，兼具有想象空间的美感。

test2023-10-18

test2023-10-18