上皮内生是眼外伤或眼前节手术后罕见的严重并发症，可导致角膜内皮失代偿、继发性青光眼或其他不良结果。其中难治性青光眼是上皮内生后眼球摘除的主要原因，因此提高对本病的认识并严加防范至关重要。本文回顾分析1例上皮内生性青光眼患者的临床资料和病理切片，结合文献讨论本病的危险因素、发病机制及防范措施。

Epithelial downgrowth is a rare yet serious complication after ocular trauma or anteriorsegmental surgery. It can lead to decompensation of corneal endothelium, secondary glaucoma or other serious complications, among which refractory glaucoma is the main cause of enucleation. It is vital to raise the awareness of this disease and take strict precautions against it. We present a case of epithelial downgrowth and discuss the risk factors, pathogenesis and preventive measures of the disease through analyzing clinical data and pathological sections.