目的：调查角膜塑形镜对近视儿童脉络膜厚度和脉络膜轮廓的长期影响。方法：受试者来自一项2年的随机对照试验。研究对象为年龄8~12岁、等效球镜在-1.00~-6.00 D的儿童(n=80)，这些研究对象被随机分配到对照组(n=40)和角膜塑形镜组(n=40)。本研究在基线和1、6、12、18、24个月的随访中收集光学相干断层扫描图像(optical coherence tomography,OCT)，然后基于OCT图像计算脉络膜厚度和脉络膜轮廓。在这些随访点也同时测量了眼轴长度(axial length,AL)和其他眼生物学参数。结果：在2年内，对照组的脉络膜厚度随时间变薄，脉络膜轮廓变得更加后凸(均P<0.001)。角膜塑形镜可以改善脉络膜厚度(均P<0.001)，并在所有随访中维持脉络膜轮廓不后凸(均P<0.05)。在角膜塑形镜组中，脉络膜轮廓在颞侧的变化小于鼻侧(P=0.008)，而脉络膜厚度在颞侧以黄斑中心凹为中心、直径3 mm线性扫描区域的增厚更明显(P<0.001)。2年内脉络膜厚度的变化与对照组中2年内AL变化呈负相关(r=-0.52，P<0.001)，然而，这一规律被角膜塑形镜打破(r=-0.05 P=0.342)。在多变量回归模型中校正其他变量后，角膜塑形镜对脉络膜厚度的影响是稳定的。结论：角膜塑形镜可以改善脉络膜厚度并维持脉络膜轮廓，但这种效果在长期内趋于减弱。

Objective: To investigate the long-term effect of orthokeratology on the choroidal thickness and choroidal contour in myopic children. Methods:Subjects were from a conducted 2-year Randomized Clinical Trial. Children (n=80) aged 8-12 years with spherical equivalent refraction of -1.00 to -6.00 D were randomly assigned to the control group (n=40) and ortho-k group (n=40). OCT images were collected at the baseline, 1-, 6-, 12-, 18-, and 24-month visits, then the choroidal thickness and choroid contour were calculated. Axial length (AL) and other ocular biometrics were also measured. Results: During two years, in the control group, the choroidal thickness became thinning and the choroidal contour became prolate with time at all visits (all P<0.001). Ortho-k can improve the choroidal thickness (all P<0.001) and maintain the choroidal contour at all visits (all P<0.05). In the ortho-k group, the choroidal contour was less changed in the temporal than nasal (P=0.008), and the choroidal thickness was more thickening in the temporal 3 mm (P<0.001). Two-year change in choroidal thickness was significantly associated with the two-year AL change in the control group (r=-0.52, P<0.001), however, this trend was broken by ortho-k (r=-0.05, P=0.342). After being adjusted by other variables in the multivariable regression model, the effect of ortho-k on choroidal thickness was stable. Conclusions: In a short term, ortho-k can improve the choroidal thickness and maintain the choroidal contour, but this effect diminished in a long term. Further study with larger sample size and longer follow-up is warranted to refine this issue.

目的：干眼已成为影响儿童和青少年眼健康的重要问题，但其流行病学特征及相关因素尚未在中国西部地区儿童和青少年群体中得到充分研究。本研究旨在调查新疆喀什地区英吉沙县学龄儿童和青少年的干眼患病率，并分析其相关因素，为儿童和青少年干眼的防治提供流行病学依据。方法：本研究为横断面研究，于2024年5—6月在英吉沙县第三中学和芒辛镇中心小学开展，共纳入3 305名在校儿童和青少年进行问卷调查，并随机抽取557名儿童和青少年进行眼表检查。采用眼表综合分析仪测量泪河高度和非接触泪膜破裂时间。干眼诊断基于世界泪膜与眼表学会发布的第二版干眼专家共识（2017）。采用多因素logistic回归分析干眼的相关因素。结果：在557名参与儿童和青少年中，干眼患病率为16.88%（94/557）。不同性别间干眼患病率比较差异无统计学意义（P=0.81）。干眼患病率随年龄增长而增加，具有显著的线性趋势。任一眼有屈光不正的儿童和青少年干眼患病率更高（29.05% vs. 12.47%，P<0.001）。多因素Logistic回归分析显示年龄（OR=1.21）和屈光不正（OR=2.72）是干眼的危险因素，性别、身体质量指数、右眼眼轴长度及父母近视情况无关。结论：新疆喀什地区英吉沙县学龄儿童和青少年的干眼患病率与全国均值相近且偏低，年龄增长和屈光不正显著增加干眼患病风险，应关注儿童和青少年屈光状态对眼表健康的影响，并采取相应的预防措施。

Objective: Dry eye (DED) has emerged as an important ocular health concern among children and adolescents. However, in pediatric populations in western China, its epidemiological characteristics and associated risk factors have not been thoroughly investigated. This study aimed to investigate the prevalence of DED and analyze its risk factors among school-age children and adolescents in Yingjisha County, Kashgar Prefecture, Xinjiang, so as to provide a solid evidence base for formulating prevention and control strategies. Methods: This cross-sectional study was conducted from May to June 2024 at Yingjisha County No. 3 Middle School and Mangxin Central Primary School. A total of 3,305 school children and adolescents completed the questionnaire, and 557 of them were randomly selected for ocular surface examinations. The Keratograph 5M was used to measure tear meniscus height (TMH) and non-invasive tear break-up time (NIBUT). DED diagnosis adhered to the Dry Eye WorkShop II 2017 (DEWS II) criteria published by Tear Film & Ocular Surface Society (TFOS). Multivariate logistic regression was applied to evaluate the associated risk factors. Results: Among the 557 children and adolescents who underwent examinations, the prevalence of DED was 16.88% (94/557). No statistically significant difference was observed between genders (P = 0.81). The prevalence of DED increased with age, showing a significant linear trend. Participants with refractive errors in either eye had a significantly higher prevalence of DED (29.05% vs. 12.47%, P< 0.001). Logistic regression analysis identified age (OR = 1.21) and refractive error (OR = 2.72) as risk factors. No significant associations were found for gender, Body Mass Index (BMI), axial length of the right eye, or parental myopia. Conclusions: The prevalence of DED among school-age children and adolescents in Yingjisha County is either comparable to or slightly lower than, the national average. Age and refractive error substantially increase the risk of DED. Greater attention should be directed towards children’s refractive status to protect ocular surface health and implement early preventive measures.

目的：探讨提高眼科喉罩全身麻醉患儿在麻醉恢复室(post-anesthesia care unit, PACU)复苏质量与效率的整体护理策略。方法：选取2020年1月—2023年12月在中山大学中山眼科中心行眼科全身麻醉并保留喉罩进入PACU复苏的24 180例患儿，总结患儿在PACU复苏的护理措施及复苏质量。结果：所有患儿经复苏期综合护理后均顺利拔除喉罩完成麻醉复苏，未发生苏醒期二次插管或非计划转院治疗。采取个性化的整体护理策略后，喉罩全身麻醉患儿PACU平均复苏时间明显缩短。部分术后常见并发症(术后躁动，低氧血症和呼吸道梗阻)和护理不良事件(留置针脱落和眼包脱落)发生率逐年降低，经治疗和护理后均获得改善。结论：针对眼科全身麻醉的患儿特点，在麻醉复苏期采取个性化的整体护理策略，有利于顺利完成麻醉复苏，降低麻醉并发症和护理不良事件的发生率，提高复苏质量效率，满足眼科日间手术快速康复的需求。

Objective: To explore holistic nursing strategies to improve the quality and efficiency of post-anesthesia care unit (PACU) resuscitation in childrenpatients undergoing ophthalmic laryngeal mask anesthesia. Methods: A total of 24,180 children patients who underwent general anesthesia and retained laryngeal mask airway for PACU resuscitation at Sun Yat-sen Ophthalmic Center of Sun Yat sen University from January 2020 to December 2023 was reviewed and summarized the nursing measures and resuscitation quality of children patients undergoing PACU resuscitation. Results: All patients underwent comprehensive care during the recovery period and successfully removed the laryngeal mask to complete anesthesia recovery. There were no cases of secondary intubation or unplanned transfer for treatment during the recovery period. After adopting personalized holistic nursing strategies, the average recovery time of PACU in children under laryngeal mask anesthesia was significantly shortened.The incidence of common postoperative complications(postoperative agitation, hypoxemia and respiratory obstruction)and adverse nursing events (indwelling needle falls off, eye bandage fall off)had been decreasing year by year. These complications had been improved after treatment and care. Conclusions: Based on the characteristics of children patients undergoing general anesthesia in ophthalmology, adopting personalized holistic nursing strategies during the anesthesia recovery period is beneficial for successfully completing anesthesia recovery, reducing the incidence of anesthesia complications and adverse nursing events, improving the quality and efficiency of recovery, and meeting the needs of rapid recovery in ophthalmic day surgery.

目的：探索一种无创的、智能可穿戴设备监测学龄儿童量化的用眼行为，并定量分析近视发生的相关因素。方法：招募佛山市禅城区石湾第二小学三年级及狮城中学小学部五年级的年龄为7~11岁部分学生共171例。所有受试者均按照非睫状肌麻痹主觉验光结果分为近视组108例和非近视组63例，所有受试者均佩戴智能可穿戴设备“云夹”，进行为期10 d(2022年9月21日—2022年10月2日)的用眼行为数据(近距离用眼距离、近距离用眼时间、近距离环境光照、有效户外时间)采集。采用t检验比较近视组与非近视组儿童在用眼行为数据之间的差异，并应用Logistic回归分析用眼行为与近视发生的相关性。绘制受试者操作特征(receiver operating characteristic curve,ROC)曲线，并计算曲线下面积(area undercurve,AUC)分析用眼行为习惯对近视发生的预测价值。结果：学龄期儿童近视患病率为63.2%。近视组与非近视组在每天用眼时间、单次用眼时间、用眼距离、白天用眼光照、晚上用眼光照、每天户外活动时间及每天有效户外活动暴露次数比较差异均有统计学意义(均P＜0.05)。Logistic回归分析显示，单次用眼时间、每天用眼时间是近视发生的危险因素。Spearman相关性分析显示，单次用眼时间及每天用眼时间均与近视发生呈正相关(均P＜0.05)。单次用眼时间预测近视发生的ROC曲线下面积为0.939。结论：可穿戴设备“云夹”可量化学龄期儿童用眼行为；学龄期儿童近视发生可能与近距离用眼时间有一定相关性；预测模型可结合儿童屈光发育档案，量化近视发生风险，对儿童实现分类管理，及时采取个性化干预。

Objective: To investigate a non-invasive,smart device capable of monitoring the quantitative visual behavior of school age children, and to analyze quantitatively the relationship between visual behavior and the occurrence of myopia. Methods: This study recruited 171 subjects aged between 7 and 11 years from the third grade of Shiwan SecondPrimary School and the fifth grade of Shicheng Middle School in Chancheng District, Foshan City. Participants werecategorized into a myopia group (108 subjects) and a non-myopia group (63 subjects) based on results from non-ciliary muscle paralysis optometry. All subjects wore "clips" to track their near-work distance, near-work duration, lighting conditions during near-work, and time spent on outdoor activities between September 21, 2020, and October 10, 2020. Differences in these habits between the myopia and non-myopia groups were compared, and logistic regression analysis was conducted to assess the impact of habitual eye use on myopia. Results: The prevalence of myopia was found to be 63.2%. Statistically significant differences (all P<0.05) were observed between the myopic and non-myopic groups regarding average daily near-work time, average single near-work session duration, average near-work distance, average daytime and nighttime near-work lighting conditions, average daily outdoor activity time, and average daily effective outdoor activity exposure. Logistic regression analysis indicated that longer average single near-work sessions and increased average daily near-work time were risk factors for myopia. Spearman correlation analysis further supported these findings, showing a positive correlation between average single near-work session duration and average daily  near-work time with the occurrence of myopia (all P<0.05). The predictive accuracy of a model combining average single near-work session duration and average daily near-work time for myopia occurrence was high, with an area under the curve of 0.939. Conclusions: The wearable device "Cloud clip" effectively monitors the visual behavior of school-age children. The occurrence of myopia in this age group may be associated with increased near-work activities. A predictive model incorporating refractive development in myopic children can assess the quantitative risk of myopia, enabling the classification and management of school-age children. Personalized interventions may serve as protective factors against myopia.

目的：评估分析新疆地区14个地州6~18岁学龄儿童青少年屈光参差的患病率、空间分布特征和影响因素，为制定区域性眼健康干预策略提供科学依据。方法：采用横断面研究设计，纳入新疆地区14个地州的小学、初中及高中学生共64 277名，收集其人口学特征、屈光状态及地域分布数据。通过等效球镜度（spherical equivalent，SE）评估屈光状态，近视为SE ≤ -0.50 D，屈光参差为眼间SE差异≥1.0 D，采用Moran's I分析屈光参差患病率的空间分布，采用单因素及多因素回归分析探讨屈光参差的危险因素。结果：屈光参差的总体患病率为17.9%（95% CI：17.6%～18.2%），女性屈光参差患病率（18.8%）高于男性（16.9%），汉族（23.9%）高于维吾尔族（11.7%）和其他民族（18.4%）（P<0.001）。屈光参差患病率呈空间聚集分布(Moran's I = 0.450，P = 0.043，Z = 2.026)，并且存在地域差异，昌吉最高（24.1%），克孜勒苏柯尔克孜自治州最低（7.9%），城市（19.0%）高于农村（15.6%），北疆（19.9%）高于南疆（13.5%）（P<0.001）。屈光参差的患病率与年龄呈正相关，6岁为9.8%，18岁达22.4%。多因素回归分析显示，女性、北疆地区、近视和较高年龄是屈光参差的独立危险因素（P<0.05）。结论：新疆地区学龄儿童青少年屈光参差患病率较高，在空间上呈聚集分布，且存在显著的人口学及地域差异，女性、北疆地区、近视和较高年龄是屈光参差的独立危险因素，建议加强对高危人群的视力筛查及早期干预。  

Objective: To evaluate and analyze the prevalence, spatial distribution characteristics, and influencing factors of anisometropia among school-aged children and adolescents aged 6-18 across 14 prefectures in Xinjiang, thereby providing a scientific foundation for formulation of regional eye health intervention strategies. Methods: A cross-sectional study design was employed, including 64,277 students from primary, middle, and high schools in 14 prefectures of Xinjiang. Data on demographic characteristics, refractive status, and geographical distribution were collected. Refractive status was assessed using spherical equivalent (SE). Myopia was defined as SE ≤ -0.50 D, and anisometropia was defined as an interocular SE difference ≥ 1.0 D. Moran's I analysis was used to evaluate the spatial distribution of anisometropia prevalence. Additionally, univariate and multivariate regression analyses were conducted to identify risk factors for anisometropia. Results: The overall prevalence of anisometropia was 17.9% (95% CI: 17.6%-18.2%). The prevalence was higher among females (18.8%) compared to males (16.9%), and higher among Han Chinese (23.9%) than among Uyghurs (11.7%) and other ethnic groups (18.4%) (P<0.001). The prevalence of anisometropia showed a spatially clustered distribution (Moran's I = 0.450, P= 0.043, Z-score = 2.026) , with notable regional variations. Changji had the highest prevalence (24.1%), while Kizilsu Kirghiz Autonomous Prefecture had the lowest (7.9%). Urban areas (19.0%) had a higher prevalence than rural areas (15.6%), and northern Xinjiang (19.9%) had a higher prevalence than southern Xinjiang (13.5%) (P<0.001). The prevalence of anisometropia was positively correlated with age, increasing from 9.8% at age 6 to 22.4% at age 18. Multivariate regression analysis showed that female gender, residing in northern Xinjiang, myopia, and older age were independent risk factors for anisometropia. Conclusions: The prevalence of anisometropia among school-aged children and adolescents in Xinjiang is relatively high, showing a spatially clustered distribution with significant demographic and regional disparities. Female gender, residing in northern Xinjiang, myopia, and older age are independent risk factors for anisometropia. It is recommended to enhance vision screening and implement early intervention for high-risk populations.

目的：调查新疆英吉沙县7~16岁儿童和青少年近视前期 ( 屈光度≤+0.75 D且>-0.50 D)患病率及其相关因素,为该地区近视防控提供依据。方法：在2024年5—6月采用简单抽样法选取新疆喀什地区英吉沙县一所中学和芒辛镇一所小学的学生进行问卷调查、视力、散瞳验光、眼轴、眼前段、眼底检查等横断面评估，分析纳入等效球镜(spherical equivalent，SE)度数较高眼的数据，采用单因素和多因素逻辑回归分析人口学特征、家族史、用眼行为、生活习惯等潜在相关因素与近视前期的关系。结果：共纳入3 247名参与者，男性占50.14%，女性占49.86%。近视前期1 652人(50.88%)，近视621人(19.12%)，非近视974人(30.00%)。近视前期患病率为50.88%(95%CI:49.16%~52.60%)，近视患病率为19.12%(95%CI:17.81%~20.51%)。多因素回归分析显示，女性(OR=2.56, 95%CI:2.09~3.13, P<0.001)、较大年龄(OR=1.19, 95%CI:1.13~1.24 , P<0.001)和较长眼轴(OR=2.68, 95%CI: 2.31~3.11 , P<0.001)是近视前期的相关因素。结论：在新疆喀什地区英吉沙县7~16岁儿童和青少年中，半数处于近视前期，其相关因素包括年龄偏大、女性及眼轴偏长。

Objective: To investigate the prevalence of pre-myopia (defined as spherical equivalent ≤+0.75 D and >−0.50 D) and its related factors among children and adolescents aged 6–16 years in Yengisar County, Xinjiang, China, providing evidence for regional myopia prevention. Methods: In May and June 2024, a comprehensive assessment was carried out on students selected through simple sampling from a middle school in Yingjisha County, Kashgar Prefecture, Xinjiang, and a primary school in Mangxin Town, Yingjisha County. ,The assessment included a questionnaire survey, visual acuity test, dilated eye refraction measurement, axial length measurement, anterior segment examination, and fundus examination. The data included eyes with high spherical equivalent (SE) power. Single-factor and multiple-factor logistic regression analyses were used to investigate the relationship between demographic characteristics, family history, eye-use behavior, lifestyle habits, and other potential related factors with pre myopia. Results: A total of 3,247 participants were included in the study, with 50.14% being male and 49.86% female. Among them, 1,652 (50.88%) individuals had preclinical myopia, 621 (19.12%) had myopia, and 974 (30.00%) had non myopia. The preclinical prevalence of myopia was 50.88% (95% CI: 49.16-52.60), and the prevalence of myopia was 19.12% (95% CI: 17.81-20.51). Multivariate regression analysis showed that female (OR=2.56, 95% CI: 2.09-3.13, P<0.001), older age (OR=1.19, 95% CI: 1.13-1.24, P<0.001), and longer axial length (OR=2.68, 95% CI: 2.31-3.11, P<0.001) were related factors in the preclinical stage of myopia. Conclusions: Among children and adolescents aged 7-16 in Yingjisha County, Kashgar Prefecture, Xinjiang, Half were in the preclinical stage of myopia. The related factors include older age, female gender, and axial length.

朗格汉斯细胞组织细胞增生症 (Langerhans cell histiocytosis,LCH) 是一种由骨髓细胞肿瘤性增殖引起的罕见疾病，多见于儿童。LCH临床表现多样，以骨骼受累最常见。该文报道了一例儿童颅眶沟通LCH，影像学检查结果提示患儿右侧眉弓处类圆形穿凿样骨质破坏，通过手术切除病灶，送组织病理学检查明确诊断，同时选择通过3D打印聚醚醚酮(polyetheretherketone,PEEK)材料修补颅眶缺损部位，PEEK材料匹配度高、安全性好，改善患儿预后，提升患儿生存质量。

Langerhans cell histiocyte (LCH) is a rare disease caused by the tumor-like proliferation of bone marrow cells, which is mostly seen in children. Its clinical manifestations can be diverse, in which the skeletal system is most involved. This paper reports a case of LCH in cranio-orbital communication of a child. The imaging results suggest that there is a round chisel damage at the patient’s right brow ridge. In terms of definitive diagnosis and treatment, this patient underwent surgical resection and histopathological examination. 3D-printed polyether-ether-ketone (PEEK) material was selected to repair the cranio-orbital defect. The material can achieve better biocompatibility, while 3D-printing technique allows higher matching degree, both help to improve the prognosis and quality of life of the patient.

目的：了解新疆喀什地区英吉沙县7~16岁儿童青少年弱视患病情况及其相关因素，为制定科学有效的眼健康防控策略提供依据。方法：选取新疆喀什地区英吉沙县3 261名在校儿童青少年，对其进行裸眼视力、最佳矫正视力、屈光度、眼位和眼底情况等检查，并通过问卷调查收集其基本人口学信息、近视家族史、用眼情况和睡眠情况，采用Logistic回归分析7~16岁儿童青少年弱视患病的相关因素。结果：英吉沙县儿童青少年弱视的患病率为1.99%（95%·CI: 1.51~2.47）。弱视患病率在学生类型、性别、近视家族史、主观睡眠质量、每天写作业时间、每天睡眠时间等方面比较差异无统计学意义（P＞0.05），在斜视、近视、远视、屈光参差、每天使用电子产品时间等方面比较差异有统计学意义（P＜0.05）。多因素回归分析结果显示，斜视、远视、屈光参差及每天使用电子产品时间与弱视相关，对应的OR值相应为3.82（95%CI: 1.93~7.58，P＜0.001）、10.88（95%CI: 4.85~24.40，P＜0.001）、13.54（95%CI:6.84~26.78，P＜0.001）和0.25（95%CI: 0.12~0.54, P＜0.001），合并斜视、远视或屈光参差的儿童青少年患弱视的风险增加。每天使用电子产品时间＞60 min的儿童青少年患弱视风险较使用时间≤60 min降低。弱视类型以屈光不正性弱视和屈光参差性弱视为主。结论：在新疆喀什地区英吉沙县7~16岁儿童青少年人群中，屈光不正和屈光参差是弱视患病的主要原因。斜视、远视、屈光参差、每天使用电子产品时间是弱视的影响因素。

Objective: To conduct a comprehensive investigation into the prevalence of amblyopia and its influencing factors among children and adolescents aged 7-16 in Yingjisha County, Kashgar Prefecture, Xinjiang. The ojective is to furnish a solid basis for formulating scientific and effective eye health prevention and control strategies. Methods: A total of 3,261 school-aged children and adolescents in Yingjisha County, Kashgar Prefecture, Xinjiang, were selected for this study. The examinations included uncorrected visual acuity, best-corrected visual acuity, refractive error, ocular alignment, and fundus condition. A questionnaire was used to collect demographic information, family history of myopia, daily eye-use habits, and sleep status. The data were analyzed using SPSS statistical software, and logistic regression was employed to explore factors associated with amblyopia in children and adolescents aged 7-16. Results: The study revealed that the prevalence of amblyopia among children and adolescents in Yingjisha County was 1.99% （95% CI: 1.51-2.47）. There were no significant differences (P > 0.05) in the prevalence of amblyopia across student type, sex, family history of myopia, subjective sleep quality, daily homework duration, or daily sleep duration. However, significant differences (P < 0.05) were observed in cases involving strabismus, myopia, hyperopia, anisometropia, and daily screen time. Multivariate regression analysis indicated that strabismus (OR = 3.82, 95% CI: 1.93-7.58, P < 0.001), hyperopia (OR = 10.88, 95% CI: 4.85-24.40, P < 0.001), and anisometropia (OR = 13.54, 95% CI: 6.84–26.78, P < 0.001) were positively correlated with amblyopia. Conversely, children and adolescents who used electronic devices for >60 minutes per day had a lower risk of amblyopia (OR = 0.25, 95% CI: 0.12-0.54, P < 0.001) compared to those with ≤60 minutes or less of daily screen time. The most common type of amblyopia was mixed amblyopia （60.00%）, followed by anisometropic amblyopia （23.08%）, refractive amblyopia （12.31%）, and strabismic amblyopia （4.62%）. Among mixed amblyopia cases, the combination of refractive amblyopia and anisometropic amblyopia was the predominant pattern （64.10%）. Conclusions: Refractive errors and anisometropia are the main causes of amblyopia. Strabismus, myopia, hyperopia, anisometropia and the duration of electronic device use are identified as influencing factors for amblyopia.

目的：评估远视儿童使用1%阿托品凝胶1周后脉络膜厚度(choroidal thickness,CT)的变化。方法：选择42例4~7岁的远视儿童，予每天使用1%阿托品凝胶两次，持续7d。使用光学相干断层成像扫描测量视网膜及CT，并分析使用1%阿托品凝胶前后中心凹以及距中心凹处间隔1.0 mm的上、下、鼻和颞侧(最多3.0mm)CT的变化。结果：在远视儿童中，基线CT随位置而变化(F=27.08, P<0.05)，与中心凹相比，鼻侧及距中心凹上方2 mm、3 mm及距中心凹颞侧3 mm处的CT较薄(P<0.05)。使用1%阿托品凝胶后，中央凹及旁中心凹CT改变比较差异无统计学意义(P＞0.05)。使用1%阿托品凝胶前后视网膜厚度无明显变化(P＞0.05)。结论：短期使用1%阿托品凝胶并没有改变远视儿童的脉络膜和视网膜厚度。

Objective: To assess changes of choroidal thickness (CT) in hyperopia children after 1 week using of 1% atropine.Methods: A total of 42 hyperopia children aged 4–7 years were included into the study.A single drop of 1% atropinegel was used twice a daily for 7 days in the subjects.The thickness of retina and choroid was measured by OCT, and the changes before and after using 1% atropine gel were analyzed at the subfovea and at 1.0 mm intervals (up to3.0 mm) from the fovea at superior, inferior, nasal, and temporal locations. Results: In the hyperopia children, baselineCT parameters were varied with the location(F=27.08,P<0.05).Compared with the fovea, the CT at the nasal side,2 mm and 3 mm above the fovea and 3 mm from the temporal side of the fovea were thinner (P<0.05).After using 1%atropine gel, there was no significant difference in the CT changes of subfoveal choroidal thickness and other sites ofparafovea (P> 0.05). There was no significant change in retinal thickness before and after using 1% atropine gel (P > 0.05).Conclusion: No changes were found in the thickness of choroid and retina in hyperopia children after short-term use of1% atropine gel.

目的：探讨一种改良的简便的儿童晶状体不全脱位摘除技术的手术方法及临床效果。方法：对23例(40眼)晶状体不全脱位儿童采用改良手术方法进行脱位晶状体摘除，术中先做巩膜隧道切口，3个角膜缘穿刺口，经穿刺口放置前房维持器，在维持前房灌注下，截囊针撕囊，水分离后抽吸针头吸净晶状体内容物。撤去前房维持器，用撕囊镊和线镊将囊袋从主切口拖出。若有玻璃体脱出则行前部玻璃体切除术，然后行人工晶状体巩膜缝线固定术。术后中位随访39.0个月，观察其手术效果。结果：术后患儿平均裸眼视力为(0.44±0.22)LogMAR，平均最佳矫正视力为(0.20±0.16)LogMAR，较术前均显著提高(P<0.001)。所有患儿术中眼内压稳定，术中术后没有继发视网膜脱离、脉络膜上腔出血等眼底并发症的发生。结论：改良的儿童晶状体不全脱位摘除技术具有对玻璃体扰动少、手术时间较短、简便易学、对手术设备要求低的优点，值得临床推广。

Objective: To investigate the operation method and clinical effects of a modified-simple technique in children with subluxated lens extraction. Methods: Lens extraction was performed in 40 eyes of 23 children. During operation, the scleral tunnel and 3 lateral corneal incision were made, and anterior chamber maintainer was inserted through one corneal incision. Under stable anterior chamber perfusion, anterior capsulorrhexis was made by needle capsulotome. After hydro-dissection, the content of lens was withdrawn by suction needle completely. Then anterior chamber maintainer was removed, and the capsular bag was dragged out by capsulorhexis forceps and fixation forceps. Anterior vitrectomy was performed if there was prolapse of vitreous. Then scleral intraocular lens fixation was performed. The surgical effects were observed at median 39.0 months postoperative. Results: After surgery, the average uncorrected visual acuity was (0.44±0.22) LogMAR, the average best corrected distant visual acuity was (0.20±0.16) LogMAR. The uncorrected visual acuity and best corrected distant visual acuity were improved postoperative(P<0.001). The intraocular pressure of all patients was stable during operation. During and after operation, there were no fundus complications, such as secondary retinal detachment and suprachoroidal hemorrhage. Conclusion: Modified-simple technique of subluxated lens extraction of children has little disturbance on vitreous and takes shorter time of operation. It is simple, easy to learn and requires simple surgical equipment. This modified technique deserves to be generalized.