Purpose : To analyze the postoperative period of patients with primary acquired nasolacrimal duct obstruction (PANDO) who underwent endoscopic dacryocystorhinostomy (En-DCR) in the day room mode of Current status of care and early outcome evaluation. Methods : Ninety patients with PANDO who underwent En-DCR surgery at the Department of Oculoplastics and Lacrimal Ducts, Zhongshan Ophthalmic Center, Sun Yat-sen University, China, from November 2021 to August 2022 were included, and they were given instructions on postoperative home medication, diet, and nasal and prosthetic duct care. One month after the operation, we returned to the hospital for nasal endoscopy, reviewed and recorded the nasal anastomosis, and used a questionnaire to record the current status of patients' postoperative care and subjective symptom improvement and lacrimal duct irrigation. Results : A total of 90 PANDO patients totaling 94 eyes were included. The mean age was 55.81 ± 12.19 years. The subjective surgical outcome was 62 eyes (70.0%) cured, 25 eyes (26.6%) improved, and 7 eyes (7.4%) ineffective. Surgical outcome was better in patients who followed postoperative nasal rinsing at least once a day, regular use of seroquelin hydrochloride with budesonide nasal spray, and did not suffer from upper respiratory tract infections (P=0.008, P<0.001, P=0.020). Local discomfort symptoms were associated with surgical outcome (R=0.43, P<0.001). Post-lacrimal duct placement discomfort was associated with higher psychological burden (R=0.39, P=0.00090). Frequency of nasal washings and presence or absence of prosthetic tubes had an effect on postoperative discomfort (P< 0.028, P< 0.043). Conclusion: Under the day ward model, healthcare professionals should provide guidance on personal care management for patients after En-DCR, including nasal rinsing at least once a day, regular use of anti-inflammatory nasal sprays and prevention of upper respiratory tract infections; they should focus on the local discomfort symptoms of patients with lacrimal duct placement in the postoperative period, and follow up on the Internet or by telephone to provide good nursing guidance and psychological counseling.