Objective To enhance the overall clinical thinking ability, we aimed to establish the LRC Stepwise Collaborative Learning Model (LRC Model) in ophthalmology training. Methods The LRC Model, centered around diseases, integrates three daily teaching activities including lectures, teaching rounds, and case discussions. Employing a progressive teaching approach, modular teaching activities were designed to meet the training requirements that seamlessly integrate student satisfaction and teaching quality. To explore its effectiveness, a quantitative analysis was conducted from April 2023 to January 2024, involving 47 ophthalmology resident physicians. Results The implementation of the LRC Stepwise Collaborative Learning Model resulted in a significant improvement in the average scores of resident physicians from pre-training [(48.08±5.67) points] to post-training [(92.31±7.10) points], with statistical significance (P<0.01). A questionnaire survey covering course design, clinical utility, content mastery, and teacher satisfaction was conducted, with each dimension rated on a scale of 5, totaling 20 points. Results indicated high satisfaction among residents for lectures [(19.65±1.09) points], teaching rounds [(19.35±1.55) points], and case discussions [(19.00±1.76) points]. Conclusion: The LRC Stepwise Collaborative Learning Model, as a new training system for residency education, has been recognized by ophthalmology resident physicians. It facilitates the overall improvement of clinical thinking, contributes to competency development, and provides valuable insights for the design and implementation of future teaching models.
AIM： To explore the effect of operating room temperature on the postoperative outcomes of femtosecond laser-assisted in situ keratomileusis (FS-LASIK). METHODS：Retrospective case-control study. Collect cases that underwent FS-LASIK in our hospital from May 2023 to October 2023. Cases were extracted with small differences in age, diopters, corneal thickness, corneal curvature, and operating room humidity.Cases with different temperatures during surgery were divided into three groups.Each group has 20 people with 40 eyes, a total of 60 people with 120 eyes. The operating room temperature in group A was 21.0-21.5°C, in group B was 22.0-22.5°C, and that in group C was 23.0-23.5°C. The surgery was completed by the same surgeon and the same equipment, and the same postoperative medication was used. The differences in naked eye visual acuity and diopters between the three groups were compared 3 months after surgery. RESULTS：Comparison of different surgical temperature groups 3 months after surgery, no statistical difference was found between naked eye visual acuity and diopters (P >0.05). The naked visual acuity and spherical equivalent refraction of the three groups 3 months after surgery did not satisfy the normal distribution, and the Kruskal-Wallis method was used to test. There was no statistical significance in postoperative naked eye visual acuity (H=2.648, P=0.266). There was no statistical significance in the postoperative spherical equivalent refraction of the three groups (H=1.010, P=0.604). CONCLUSION： Only significant changes in temperature and humidity in the air can have a significant impact on excimer laser energy. Humidity may have a greater impact than temperature. The results of this study did not found that changes in the temperature range recommended by the equipment manufacturer have a statistically significant impact on the visual acuity and diopters after FS-LASIK. KEYWORDS： Operating room temperature; Operating room humidity; Femtosecond laser-assisted in situ keratomileusis .
【Abstract】Objective To investigate the clinical effect of the traditional Chinese medicine aerosol with androgen-like effect on the ocular surface inflammatory indicators in patients with dry eye. Methods A total of 50 patients (6 cases dropped out) were randomly divided into two groups by random number method, with 25 cases in each group (23 cases in the experimental group and 21 cases in the control group). They were treated with traditional Chinese medicine aerosol solution and saline solution every other day for 7 times, with a total duration of 14 days.The tear fluid was collected before and after the experiment, and the concentrations of IL-1β and TNF-α were detected by ELISA method.The eye redness index was collected by eye surface comprehensive analyzer before and after the experiment, and the eye redness degree was divided into 0-4 grades according to the percentage of vascular area and total area. Results Under the conditions of this experiment, there was no significant change in the expression levels of ocular surface inflammatory factors IL-1β and TNF-α before and after treatment, but the eye redness index decreased significantly. Conclusion The use of traditional Chinese medicine aerosol with androgen-like effect on the ocular surface has a certain inhibitory effect on the inflammatory response of dry eye, and its mechanism deserves further exploration.It is expected to become a new method for anti-inflammatory treatment of dry eye patients.
Red light is visible light with a wavelength range of 620-760 nm, which has both photochemical and thermal effects. It has been widely used in the field of ocular disease for its excellent performance with the development of photobiomodulation therapy. The irradiation of red light can activate cytochrome C oxidase in mitochondria, promote production of ATP and improve retinal hypoxia. It can also induce the synthesis and release of NO, cause the expansion of choroidal vessels with increase of blood flow, and increase scleral strength by remodeling of scleral extracellular matrix. It will enhance the excitability of cone cells and strengthen the central fixation function of macula. In addition, red-light therapy can reduce oxidative stress, inflammation and apoptosis in the regulatory pathways of photoreceptor cells, reduce ocualr inflammation and pain, and repair peripheral nerves after injury. This article will review the mechanism, effectiveness and safety of red-light therapy in myopia control, amblyopia treatment, retinal diseases and eyelid skin-related diseases.
Objective: To investigate the advances and trends of heat shock proteins in ophthalmology published from 2003 to 2013. Methods: The Web of Science database was used to retrieve the literature on heat shock proteins in ophthalmology published from January 1, 2003 to December 26, 2023. Bibliometric methods and VOSviewer and CiteSpaces software were used to analyze and visualize data, including publication count, countries, organizations, journals, authors, keywords and subject categories. Results: A total of 1079 publications related to heat shock proteins in ophthalmology were included, and the overall number of publications was fluctuating. The United States (n=394) was the leading contributor among countries. Investigative Ophthalmology & Visual Science (n=80) was the journal with the largest number of publications. Glaucoma and retinal ganglion cells, gene and protein expression, crystallin and cataract was identified as the research hotspots. Glaucoma, cholesterol, and molecular chaperones was identified as frontier research topics. Biochemistry, multidisciplinary science, and cell biology have the highest betweenness centrality values of 0.60, 0.28, and 0.26, respectively. Multidisciplinary Chemistry (burst years: 2017 to 2023; strength = 6.3) was a subject involved in the research frontier of this field. Conclusion: Research on heat shock proteins in ophthalmology mainly focuses on revealing the genetic background of the diseases and exploring the molecular mechanisms and therapeutic applications in glaucoma and cataracts. The advance in the study on molecular mechanisms in this field depends on multidisciplinary collaboration.
