Objective: To optimize the follow-up approach of patients with ophthalmic genetic diseases through informational technology, reduce the loss rate of cases, and help the efficient operation of the clinical laboratory. Methods: Based on the official account of Wechat, “Pediatric Genetics of Zhongshan Ophthalmic Center ", an ophthalmic genetics case management system was established, which had the functions of collecting cases, signing informed consent online, and reporting queries. According to whether the case management system was used or whether the personnel movement was restricted, patients who came to the hospital for gene testing from July 1, 2017, to November 30, 2023, were divided into four groups: traditional group, traditional+ movement restricted group, WeChat+ movement restricted group, and WeChat group. A chi-square test evaluated the performance of the case management system. Results: A total of 10662 patients were included. After using the genetics case management system, the loss rate of cases decreased from the highest 12.2% (traditional+ movement restricted group) to the lowest 1.8% (WeChat group), and the difference was statistically significant (P<0.001). The second visit rate of patients decreased from the highest, 70% (traditional group) to the lowest, 11.7% (WeChat group), and the difference was statistically significant (P<0.001). Conclusion: The use of the genetic case management system significantly reduces the loss rate of cases and the rate of second visits in patients with ocular genetic diseases.
Objective: To investigate the application and teaching effect of clinical guidelines combined with team based learning(TBL) teaching courses in standardized training for ophthalmic residents. Methods: 15 residents who received standardized training in the ophthalmology department of the First Affiliated Hospital of Guangzhou Medical University were recruited from January 2022 to June 2023. Self-study teaching and TBL teaching were successively applied to teach the clinical guidelines of ophthalmology. The subjective and objective teaching effects were evaluated by satisfaction questionnaire, passing rate of phase examination, achievement of academic proficiency test and passing rate of final examination. Results: The clinical guidelines enjoy the high opinion in the residents, and would not be strengthen their learning burden. After the residents studied clinical guidelines, their passing rate of the phase exam, academic proficiency test and final examination were all 100%. In terms of cultivating teamwork ability and study atmosphere, the satisfaction of TBL lectures was significantly higher than that of self-study lectures (P< 0.001). 93.3% (14/15) of the residents preferred TBL lectures. Conclusions: The combination of ophthalmology clinical guidelines and TBL teaching was proved to be an effective teaching model. The residents achieved excellent teaching results in the subjective satisfaction questionnaire and objective examination scores.
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Objective The aim of the research was to explore the clinical manifestations and gene mutation types of congenital choroideremia patients. It could broaden the understanding of rare hereditary eye diseases for clinical workers. Methods The clinical manifestations, imaging features and genetic analysis of these patients were retrospectively analyzed. Results The fundus manifestations of the patients were diffuse retinal atrophy, choroidal deficiency, white sclera exposed, pigment disorder, pale optic disc, C/D 0.3, and fundus blood vessels were thin and rigid. Genetic testing found there was CHM gene mutation in these patients. The main clinical manifestations were progressive loss of visual acuity with night blindness and severe visual field loss. Genetic test found that both patients with choroidosis had CHM gene mutation and the mutation sites had not been clinically reported. Conclusion The two patients were diagnosed with congenital choroidosis based on the medical history, clinical presentation and genetic testing results.
Objective: To summarize and analyze the causes and management of ocular complications caused by retrobulbar injection. Methods: A retrospective case series study. Collect clinical data of 7 patients with ocular complications caused by retrobulbar injection in our department from August 2015 to August 2023. We analyzed the causes of complications in these cases, the intraoperative situation, and the postoperative follow-up results. Results: The average age of the 7 patients was 57.57 years old ±7.55 years old, including 5 males. There were 2 cases with high myopia. All the 7 patients were prepared for carrying out posterior surgery. Two patients suffered from retrobulbar bleeding, one patient suffered from transient amaurosis during surgery, two had postoperative temporary extraocular muscle paralysis, one experienced transient ptosis, and the most severe complication was globe puncture combined with massive subomental bleeding. During the surgery, omental incision and clearance of subretinal blood accumulation were performed. After active treatment, the prognosis of all patients was satisfactory. Conclusion: Retrobulbar injection can cause many complications, with a focus on prevention. Timely and appropriate treatment can reduce eye damage.
Implantable collamer lenses (ICL), as a method of myopia correction, can be used for the refractive correction of patients who are not suitable for corneal refractive surgery, and has the advantage of "reversibility", which is chosen by more and more clinicians and patients. This procedure has been chosen by more and more clinicians and patients because of its "reversibility" advantage. In this procedure, in addition to calculating the accuracy of the refractive correction, the selection of the appropriate size of ICL is crucial to obtaining the desired postoperative results, as most of the postoperative complications of this procedure are related to suboptimal ICL size. In this article, we present a systematic review of the current studies related to ICL size selection with the aim of contributing to the evaluation of postoperative safety.
Implantable collamer lenses (ICL), as a method of myopia correction, can be used for the refractive correction of patients who are not suitable for corneal refractive surgery, and has the advantage of "reversibility", which is chosen by more and more clinicians and patients. This procedure has been chosen by more and more clinicians and patients because of its "reversibility" advantage. In this procedure, in addition to calculating the accuracy of the refractive correction, the selection of the appropriate size of ICL is crucial to obtaining the desired postoperative results, as most of the postoperative complications of this procedure are related to suboptimal ICL size. In this article, we present a systematic review of the current studies related to ICL size selection with the aim of contributing to the evaluation of postoperative safety.
A case of laser induced macular damage (LIM) caused by 808nm infrared laser irradiation is a retinal lesion caused by laser energy after laser irradiation of the eye. In the past decade of clinical work, there has been a sharp increase in reported cases of laser induced macular damage. This article reports a 24-year-old male patient who experienced blurred vision in the left eye within one week after being irradiated with an 808nm infrared laser during the experiment. The diagnosis was made through ophthalmic examination as laser induced macular injury in the left eye. After diagnosis, it is recommended that the patient take Maizhiling tablets (dosage: 300mg orally, twice a day) and lutein orally. After 5 months of follow-up, the left eye vision was 0.2, and there was no significant improvement in vision. This case is caused by laser induced macular damage. When the laser is irradiated on the eye and transmitted to the retina through the refractive medium, it is mainly absorbed by the melanin of the retinal pigment epithelium (RPE) and the outer retina, leading to retinal damage. The macular area is the most vulnerable area to damage, and the severity of the damage mainly depends on the laser intensity, irradiation time, and irradiation frequency. The article reviews the progression of the disease in this case and summarizes the clinical characteristics and diagnosis and treatment of laser induced macular injury cases reported in other literature. Intended to provide ophthalmologists with early diagnosis and treatment strategies for this type of disease.
