Aims: To investigate the relative risk of pretransplant corneal vascularisation on rate of rejection and graft failure within 5 years of surgery when categorised by indication for transplantation. Methods: We analysed all adults recorded in the UK transplant registry who had a first cornea transplant for keratoconus (KC), pseudophakic bullous keratopathy (PBK) or previous infection (viral/bacterial/fungal/protozoan) between 1999 and 2017. We analysed the number of quadrants of the recipient cornea vascularised before transplant and type of vascularisation, the interval post- transplant to rejection, if any, and the outcome at 5 years post-transplant. Risk factors for rejection and transplant failure were modelled by multivariable risk-adjusted Cox regression. Results: Corneal vascularisation was recorded in 10%, 25% and 67% of patients with KC, PBK and infection, respectively. Individuals with PBK had an increased hazard of transplant rejection only when there were more than two quadrants of vascularisation (HR 1.5, p=0.004) when either superficial and/or deep vascularisation was present (HR 1.3 and 1.4, respectively, p=0.004). Individuals who had a transplant for previous infection had an increased hazard of rejection with four quadrants of vascularisation (HR 1.6, p=0.003). There was no risk-adjusted increase in transplant failure associated with vascularisation in any group. There was weak evidence of reduction in risk of rejection and/or failure associated with lamellar compared with penetrating transplantation in KC and PBK in vascularised recipient corneas. Conclusion: Vascularisation is a risk factor for corneal allograft rejection within 5 years. The indication for transplantation has a clinically significant effect on the magnitude of this risk.

Objective To understand the current situation and changing trend of low vision among school aged children aged 6-12 in Karamay, Xinjiang, from 2016 to 2021, and provide direction and reference for the prevention and control of low vision. Methods The visual acuity monitoring data of 6~12 years old school children in Karamay urban area from 2016 to 2021 were collected randomly. The detection rate of low vision in different years, genders, nationalities and age groups in Karamay was analyzed systematically, and the comparison and trend analysis were carried out. Results From 2016 to 2021, the detection rate of low vision among school-age children in Karamay City was 30%, 21.8%, 21.4%, 34.4%, 36.4% and 34.3% respectively, showing an overall upward trend. The detection rate of low vision over the years was slightly higher in girls than in boys (P>0.05), and that of Han children was higher than that of minority children. Middle age group>low age group>high age group. The detection rate of low vision among students of different gender, nationality and age groups showed an upward trend (P<0.01), and the increase rate of girls (19.9%) was higher than that of boys (9.03%), the increase rate of minority children (25.4%) was higher than that of Han children (20.5%), and the increase rate of middle age children (21.8%) was higher than that of low age children (16.4%) and high age children (4.1%). Conclusion The detection rate of low vision in school age children in Karamay City has differences between ethnic groups and age groups, and shows a trend of low age development, focusing on the visual health of children after the age of 10; The rate of poor vision is on the rise. We should continue to strengthen screening, prevention and control to improve the visual health level of school-age children.

Infrared laser induced fundus disease (laser induced fundus disease) is a fundus lesion caused by laser energy after infrared laser irradiation of the eye.With the advancement of science and technology, infrared laser is widely used in all walks of life, so the cases of infrared laser induced fundus disease are increasing year by year.Since infrared laser beams do not elicit a visual response, victims are often unaware of the exposure unless they experience eye symptoms, resulting in patients usually not seeking medical attention immediately after the injury.The current study shows that all patients with this disease have decreased visual acuity, and various manifestations such as hemorrhages in various layers of the retina, inner retinal defects, and strong reflections in the outer retina can be seen in the acute stage, and macular edema, macular precursor, and vitreous blood can be seen in the late follow-up.The article analyzes relevant studies on infrared laser-induced fundus injury at home and abroad in recent years, and gives a review of the clinical manifestations of infrared laser-induced fundus injury, the corresponding pathological changes in the fundus, and the progress of research on the treatment and prognosis of laser-induced fundus injury.

Laser induced macular disease (LIM) is a fundus lesion caused by laser energy after laser exposure to the eye.In the last decade of clinical work, there has been a dramatic increase in reported cases of laser-induced macular damage.In this article, we report a case of a 24-year-old male patient who was diagnosed with laser traumatic macular injury in the left eye after being irradiated by an 808 nm infrared laser in his left eye while performing an experiment, and he realized that he had blurred vision in his left eye within 1 week, and he was diagnosed with laser traumatic macular injury in his left eye after an ophthalmologic examination.After diagnosis, the patient was advised to take Mai Zhi Ling tablets (usage: 300mg orally twice a day), oral lutein, etc. At the follow-up examination 5 months later, the visual acuity of the left eye was 0.2, and there was no significant improvement in the visual acuity.The case was a macular injury caused by laser. When laser irradiation in the eye and transmitted to the retina through the refractive medium, it is mainly absorbed by the melanin of the retinal pigment epithelium (RPE) and the outer retina, resulting in damage to the fundus of the eye, with the macula being the most susceptible to damage, and the severity of the damage depends mainly on the intensity of the laser, the irradiation time, and the frequency of irradiation.The article reviews the course of the case and summarizes the clinical features and diagnosis and treatment of other cases of laser-induced macular damage reported in the literature.It aims to provide ophthalmologists with ideas for early diagnosis and treatment of such diseases.

Objective: To analyze the satisfaction of five-year undergraduate students in Central South University with ?clinical?noviciate?teaching?of?ophthalmology?which?combined?application?of?various?teaching?models and explore directions for promotion, in order to continuously improve the clinical?noviciate?course. Methods: Taking the five-year undergraduate students of Central South University as the object, we analyzed diversified teaching models in clinical noviciate teaching of ophthalmology?and?get?feedback?of?satisfaction?through?questionnaires. Results: The five-year undergraduate medical students were satisfied with teaching models and the practice effect of diversified teaching models in clinical noviciate teaching of ophthalmology. Conclusion: Diversified?teaching?models?help?solidify?the?specialty?knowledge?of?ophthalmology，but?still?need?to?reform?and?improve. Artificial Intelligence (AI) can be fully applied to empower ophthalmology practice teaching, and more attention should be paid to the integration of ideological and political education under this background to cultivate professional ophthalmologist in the new era.

In recent years, artificial intelligence (AI) has been widely spread in many fields including medical education, which has had a profound impact on the development of society. As an integral part of medical education, ophthalmology teaching requires ophthalmic knowledge training and moral education keeping pace with each other. Construction of curriculum ideology and politics is a critical part of medical education, and also an effective way to foster virtue and cultivating high-quality compound and innovative talents. How to integrate ideological and political teaching into ophthalmology courses in the AI era is an important task in the construction of the ideological and political education system of ophthalmology courses. Based on the current situation of ophthalmology teaching, we analyzed the opportunities and challenges faced by ideological and political education in ophthalmology courses under the background of AI, and explores multi-dimensional improvement methods, aiming to achieve the effective integration of modern ophthalmology courses and ideological and political education, and provide new ideas for cultivating professional ophthalmologist with humanistic spirit in the new era.

As an important feature In the present age, artificial intelligence (AI) had a profound impact on many fields, including medical education. As an integral part of medical education, ophthalmology teaching requires that ophthalmic knowledge training and moral education should be kept pace with each other. Fully promoting the construction of ideological and political courses is a strategic measure to implement the fundamental task of fostering virtue and cultivating high-quality, compound and innovative talents. How to integrate ideological and political teaching into ophthalmology courses in the AI era is an important task in the construction of the ideological and political education system of ophthalmology courses. Based on the current situation of ophthalmology teaching, we analyzed the opportunities and challenges faced by ideological and political education in ophthalmology courses under the background of AI, and explores multi-dimensional improvement methods, aiming to achieve the effective integration of modern ophthalmology courses and ideological and political education, and provide new ideas for cultivating professional ophthalmologist with humanistic spirit in the new era.

Objective: To optimize the follow-up approach of patients with ophthalmic genetic diseases through informational technology, reduce the loss rate of cases, and help the efficient operation of the clinical laboratory. Methods: Based on the official account of Wechat, “Pediatric Genetics of Zhongshan Ophthalmic Center ", an ophthalmic genetics case management system was established, which had the functions of collecting cases, signing informed consent online, and reporting queries. According to whether the case management system was used or whether the personnel movement was restricted, patients who came to the hospital for gene testing from July 1, 2017, to November 30, 2023, were divided into four groups: traditional group, traditional+ movement restricted group, WeChat+ movement restricted group, and WeChat group. A chi-square test evaluated the performance of the case management system. Results: A total of 10662 patients were included. After using the genetics case management system, the loss rate of cases decreased from the highest 12.2% (traditional+ movement restricted group) to the lowest 1.8% (WeChat group), and the difference was statistically significant (P<0.001). The second visit rate of patients decreased from the highest, 70% (traditional group) to the lowest, 11.7% (WeChat group), and the difference was statistically significant (P<0.001). Conclusion: The use of the genetic case management system significantly reduces the loss rate of cases and the rate of second visits in patients with ocular genetic diseases.

Objective: To investigate the application and teaching effect of clinical guidelines combined with team based learning(TBL) teaching courses in standardized training for ophthalmic residents. Methods: 15 residents who received standardized training in the ophthalmology department of the First Affiliated Hospital of Guangzhou Medical University were recruited from January 2022 to June 2023. Self-study teaching and TBL teaching were successively applied to teach the clinical guidelines of ophthalmology. The subjective and objective teaching effects were evaluated by satisfaction questionnaire, passing rate of phase examination, achievement of academic proficiency test and passing rate of final examination. Results: The clinical guidelines enjoy the high opinion in the residents, and would not be strengthen their learning burden. After the residents studied clinical guidelines, their passing rate of the phase exam, academic proficiency test and final examination were all 100%. In terms of cultivating teamwork ability and study atmosphere, the satisfaction of TBL lectures was significantly higher than that of self-study lectures (P< 0.001). 93.3% (14/15) of the residents preferred TBL lectures. Conclusions: The combination of ophthalmology clinical guidelines and TBL teaching was proved to be an effective teaching model. The residents achieved excellent teaching results in the subjective satisfaction questionnaire and objective examination scores.

1. Scope of application (a) When you register for this website account, you provide personal registration information according to the requirements of the website; (b) The information on your browser and computer that this website automatically receives and records when you use the web services of this website or visit the Web pages of this platform, including but not limited to your IP address, the type of browser, the language used, the date and time of access, software and hardware characteristics information and the web records you require; (c) Personal data of users obtained by this website from business partners through lawful means. (d) Users of this website are strictly prohibited from Posting objectionable information, such as nudity, pornography and profane content. We will review the content posted and disable all permissions of the user once found to be objectionable. 2. Use of information (a) This website will not provide, sell, rent, share or trade your personal login information to any unrelated third party. If we store repairs or upgrades, we will send a push message to notify you in advance, please allow this page message notification in advance. (b) This website also does not allow any third party to collect, edit, sell or distribute your personal information by any means. If any user of this website engages in the above activities, once found, this website has the right to immediately terminate the service agreement with the user. (c) For the purpose of serving users, this website may provide you with information of interest to you through the use of your personal information, including but not limited to sending you information about products and services, or sharing information with partners of this website so that they can send you information about their products and services (the latter requires your prior consent) 3. Information disclosure Under the following circumstances, this website will disclose your personal information in whole or in part according to your personal wishes or the provisions of the law: (a) We will not disclose to third parties without your prior consent; (b) Share your personal information with third parties in order to provide the products and services you have requested; (c) disclose to third parties or administrative or judicial bodies in accordance with the relevant provisions of the law or at the request of administrative or judicial bodies; (d) If you have violated the relevant laws and regulations of China or this web service agreement or relevant rules, need to disclose to a third party; (e) If you are a qualified IP complainant and have filed a complaint, disclose it to the respondent at the request of the Respondent so that the parties can deal with possible disputes over rights; 4. Information storage and exchangeThe information and data collected about you on this website will be saved on the server of this website and (or) its affiliated companies, and such information and data may be sent to your country, region or overseas where the information and data collected on this website are located and will be accessed, stored and displayed overseas. 5. Use of cookies (a) If you do not refuse to accept cookies, the website will set up or access cookies on your computer so that you can log in to or use the website platform services or features that rely on cookies. The use of cookies on this website can provide you with more thoughtful personalized services, including promotional services. (b) You have the right to choose to accept or reject cookies. You can refuse to accept cookies by modifying your browser Settings. However, if you choose not to accept cookies, you may not be able to log in to or use the Web services or features that rely on cookies. (c) This Policy applies to information obtained through cookies on this website. 6. Changes to this Privacy Policy