Objective: To investigate the imaging features of fundus fluorescein angiography in central areolar choroidal
dystrophy at different stages. Methods: Ocular examination and fundus fluorescein angiography were carried
out, imaging features of fundus ffuorescein angiography were retrospectively analyzed. Results: Stage I: fundus
photography showed mild macular pigment disorders, which was involved with the fovea. Fundus fluorescein angiography (FFA): high fluorescence was close to the fovea, the area and the extent of RPE and choroidal
capillaries atrophy were insufffcient to see through the thick choroidal vessels beneath. Stage II: fundus showed
a round of low pigment area, fluorescein angiography showed high fluorescence corresponding region, with
the angiography procedure the ffuorescein leakage could be observed. Stage III: boundaries of macular atrophy
lesions were unclear which showed part of a clear boundary, stable completely atrophy lesions. FFA: part of
retinal pigment epithelium (RPE) and choroidal uncompletely atrophy surrounded was visible, in the late of
angiography choroidal atrophy capillary leakage could be seen. Stage IV: boundary of macular retinal choroidal
atrophy was clear, foveal involvement. FFA: choroidal atrophy lesions were clear which could be seen through
the thick choroidal vessels. Fluorescein leakage disappeared and the disease was stable. Conclusion: The extend
of choroidal atrophy in fundus ffuorescein angiography is an important indictor reflecting the progression of
different stages.
