The graded management of antibacterial drugs is a core strategy within the framework of Antibacterial stewardship. The topical ocular application of antibacterial drugs represents the most prevalent treatment approach for infectious eye diseases. However, at present, there are no specific regulations governing the graded management of antibacterial drugs administered via topical ocular routes. To standardize the management of topical ocular antibacterial drugs, further enforce the graded management system for the clinical use of antibacterial drugs, encourage the rational clinical application of these drugs, effectively curb bacterial resistance, and ensure both medical quality and safety, the Ophthalmology Pharmacy Expert Committee of the Guangdong Provincial Pharmacists Association Pharmaceutical Association organized relevant experts to establish this consensus based on existing provincial regulations for the graded management of antibacterial drugs after rigorous discussions. This consensus sets forth a standard graded management framework for topical ocular antibacterial drugs in ophthalmology.