目的：评价StarEyes 900(万灵帮桥，中国)与IOLMaster 500(蔡司，德国)2种眼科光学生物测量仪测量健康受试者眼部参数的差异性、相关性及一致性。方法：前瞻性观察2021年6月至7月于中山大学中山眼科中心进行眼部检查的62例健康受试者共124只眼，分别通过StarEyes 900与IOLMaster 500完成眼轴长度(axial length，AL)、最小角膜屈光力径线上角膜曲率(keratometry for the flattest meridian，Kf)、最大角膜屈光力径线上角膜曲率(keratometry for the steepest meridian，Ks)、平均角膜曲率(mean keratometry，Km)、角膜白到白直径(white-to-white corneal diameter，WTW)等参数的测量，采用配对t检验、Pearson相关分析和Bland-Altman法对其测量结果的差异进行评价。结果：StarEyes 900与IOLMaster 500测量的AL分别为(24.18±1.08) mm和(24.16±1.08) mm；Kf分别为(42.84±1.65) D和(43.04±1.57) D；Ks分别为(44.34±1.90) D和(44.17±1.80) D；Km分别为(43.59±1.73) D和(43.61±1.64) D；WTW分别为(11.64±0.29) mm和(11.64±0.30) mm。StarEyes 900与IOLMaster 500在测量Km、WTW时，其差异无统计学意义(P>0.05)，而在AL、Kf、Ks的测量上差异有统计学意义(P<0.01)。其中StarEyes 900所测的AL和Ks值大于IOLMaster 500，而Kf、Km和WTW值则小于IOLMaster 500。经Pearson相关分析，2种仪器的测量结果均表现出较高的相关性；经Bland-Altman法评价，2种仪器的测量结果均表现出较高的一致性。结论：StarEyes 900与IOLMaster 500测量的Km、WTW均表现出较高的一致性，2种方法可互为参考；测量的AL、Kf、Ks存在的差异具有统计学意义；各项参数的测量均具有较好的相关性和一致性。

Objective: To evaluate the difference, correlation and agreement of eye parameters measured by StarEyes 900 visual function analyzer (Wan Ling Bang Qiao, China) and IOLMaster 500 (Carl Zeiss, Germany) swept-source optical coherence tomography biometer. Methods: A prospective study was designed involving 62 healthy subjects (124 eyes) undergoing ophthalmic examinations in Zhongshan Ophthalmic Center from June 2021 to July 2021. Data from their both eyes were selected for analysis in all patients. Axial length (AL), keratometry for the steepest meridian (Ks), keratometry for the flattest meridian (Kf), mean keratometry (Km) and corneal diameter (WTW) were measured by the StarEyes 900 visual function analyzer and IOLMaster 500 swept-source optical coherence tomography biometer. A paired t-test was used to analyze the differences in measurement results. The Pearson correlation coefficient was used to analyze the correlation. Bland-Airman method was used to assess the agreement of the instruments. Results: The AL, Kf, Ks, Km and WTW obtained by StarEyes 900 and IOLMaster 500 were (24.18±1.08) mm and (24.16±1.08) mm, (42.84±1.65) D and (43.04±1.57) D, (44.34±1.90) D and (44.17±1.80) D, (43.59±1.73) D and (43.61±1.64) D, and (11.64±0.29) mm and (11.64±0.30) mm, respectively. The Km and WTW of the two devices showed no significant difference (P>0.05), while the AL, Ks and Kf showed significant differences (all P<0.01). The AL and Ks obtained by StarEyes 900 were higher than by IOLMaster 500, while the Kf, Km and WTW were lower. The measurements of five aforementioned biometric parameters by both devices showed good correlation by Pearson correlation coefficient and good agreement by Bland-Airman. Conclusion: The Km and WTW measured by the two devices showed no significant difference, and provided references to one another. The difference in AL, Kf and Ks between the two devices showed significant differences. All of the measurements showed good correlation by Pearson correlation coefficient and good agreement by Bland-Airman.