综述

人工智能在眼病筛查和诊断中的研究进展

Research progress of artificial intelligence in screening and diagnosis of eye diseases

:208-213
 
近年来随着人口老龄化的发展、人群用眼方式的改变,现有的眼科医疗资源正越来越难以满足日渐增长的医疗需求,亟需新型的诊疗模式予以补足。眼科人工智能作为眼科领域的新兴元素,在眼病的筛查诊断中发展迅速,主要表现为“眼部图像数据+人工智能”的模式。近年来,随着该模式在白内障、青光眼、糖尿病性视网膜病变(diabetic retinopathy,DR)等常见病中研究的深入,相关技术日渐成熟,表现出了较大的应用优势与应用前景,部分技术甚至成功转化并被逐渐应用于临床。眼科诊疗向智慧医学模式的过渡,有望缓解日益增长的医疗需求与紧缺的医疗资源之间的矛盾,从而提高整体的医疗服务水平。
The development of population aging and changes in the way people use their eyes over the recent years have increasingly challenged the existing ophthalmic medical resources to meet the growing medical needs, thus urgently calling for a novel diagnostic and treatment mode. Despite its status as an emerging sector in ophthalmology, ophthalmic artificial intelligence has developed rapidly in the screening and diagnosis of eye diseases, as can be seen in practices adopting the “eye imaging data + AI” mode. In recent years, with the intensified research on this mode with respect to common diseases such as cataract, glaucoma and diabetic retinopathy, relevant technologies have grown increasingly mature, presenting undeniable application superiority and prospects. Some of the relevant technical achievements have also been successfully transformed for practical usage, and are gradually being applied to clinical practices. Ophthalmic diagnosis and treatment are transitioning toward the era of intelligent medical services, which are expected to reduce the contradictions between the growing medical needs and the shortage of medical resources, as well as ultimately improve the overall experience of medical services.
综述

人工智能在眼科药物研发的契机与挑战

Opportunities and challenges of artificial intelligence in ophthalmic drug discovery and development

:595-602
 
近年来随着人类生活方式的改变、用眼频率的增加,眼科药物的市场需求持续增长,但是目前眼病治疗仍面临“缺医少药”的困境。由于新药研发面临成本高、周期长、成功率低的风险,眼科药物创新迭代的进程日趋缓慢。人工智能(artificial intelligence,AI)作为一种全新的技术手段,有望赋能眼科药物研发的全过程,包括药物靶点发现、化合物筛选、药物动力学模型创新与临床试验开展等,以期为眼科药物研发“降本增效”。且随着大数据体系的完善、硬件计算力的提升以及生命科学与智能科学的深度融合,AI在眼科药物研发中的作用将进一步得到提升,助力眼科药物研发实现从精准化到智能化的跨越。
With the change of human lifestyle and overuse of eyes in recent years, the market demand for ophthalmic drugs continues to grow. However, the ocular therapy is still facing the shortage of doctors and drugs. Due to the risk of high cost, long lead time and low success rate, the process of novel ophthalmic drug innovation and iteration is getting slower. As an emerging technology, artificial intelligence is expected to enable the whole process of ophthalmic drug discovery and development, including drug target discovery, compound screening, pharmacokinetic model innovation and clinical trials, thus reducing R&D costs and increase efficiency for ophthalmic drug discovery and development. In addition, with the improvement of big data, hardware calculation and the deep integration of life science and intelligent science, the role of artificial intelligence in ophthalmic drug discovery and development will be significant improved , contributing to achieve the leap from precision to intelligence.
其他期刊
  • 眼科学报

    主管:中华人民共和国教育部
    主办:中山大学
    承办:中山大学中山眼科中心
    主编:林浩添
    主管:中华人民共和国教育部
    主办:中山大学
    浏览
  • Eye Science

    主管:中华人民共和国教育部
    主办:中山大学
    承办:中山大学中山眼科中心
    主编:林浩添
    主管:中华人民共和国教育部
    主办:中山大学
    浏览
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