目的:分析发生于眶骨的占位性病变的CT表现及其与组织病理学之间的关系。方法:回顾性收集15例经临床表现、影像学特征、病理证实为发生于眶骨占位病变患者的临床资料,分析其CT检查、组织病理学切片及其他临床表现。结果:在15例患者中,经病理诊断为骨瘤的患者有4例,骨内血管瘤3例,骨样骨瘤和骨化性纤维瘤各2例,嗜酸性肉芽肿3例,尤文肉瘤1例。骨瘤由成熟板层骨构成,对应在CT上呈现为高密度的骨样结节状隆起;骨内血管瘤病理主要表现为骨小梁间的畸形血管,在CT上表现为典型的“栅栏状”“蜂窝状”特征;骨样骨瘤以骨样组织和结缔组织为主,在CT上为类圆形的高密度影,中央为典型的低密度“瘤巢“影,外周为增生的骨密度影;骨化性纤维瘤由增生的纤维组织及骨样组织构成,CT表现为肿瘤表面常有骨壳包绕,病变多呈圆形或椭圆形;嗜酸性肉芽肿主要由大量朗格汉斯细胞组成,对应CT上的软组织肿块影,可伴溶骨性破坏;尤文肉瘤以低分化的小圆细胞为主,CT表现为虫蚀样骨质破坏,破坏的骨组织间有软组织病变。结论:发生于眶骨的各类病变有其特有的病理组成,不同的病理组成在CT上表现出相应的影像特征。
Objective: To analyze computed tomography (CT) manifestations of space-occupying lesions of the orbital bone and their relationship with histopathology. Methods: The clinical data of 15 patients with orbital bone occupying lesions confirmed by clinical manifestations , imaging features and pathological symptoms features were retrospectively collected, and their CT examination, histopathological sections and other clinical manifestations were analyzed. Results: Among the 15 patients, 4 cases were pathologically diagnosed with osteoma, 3 cases of intraosseous hemangioma, 2 cases of osteoid osteoma and 2 cases of ossifying fibroma, 3 cases of eosinophilic granuloma and 1 case of Ewing’s sarcoma. Osteoma was composed of mature lamellar bones, which corresponded to a high-density osteoid nodular protuberance on CT. The pathological features of intraosseous hemangioma were mainly malformed blood vessels between bone trabeculae and typical “fence” and “honeycomb” features on CT. Osteoid osteoma was mainly composed of bone-like tissue and connective tissue, mainly showing round high-density shadow, typical low-density “tumor nest” shadow in the center, and hypertrophic bone density shadow in the periphery. Ossifying fibroma was composed of proliferative fibrous tissue and bone-like tissue. CT showed that the surface of the tumor was often surrounded by bone shell, and the lesions were mostly round or oval. Eosinophilic granuloma was mainly composed of a large number of Langerhans cells, which corresponded to the soft tissue mass on CT and could be accompanied by osteolytic destruction. Ewing’s sarcoma was mainly composed of poorly differentiated small round cells, and CT manifestations were worm-eaten bone destruction with soft tissue lesions between destroyed bone tissues. Conclusion: Various lesions occurring in the orbital bone have their own special pathological composition. Different pathological components show corresponding imaging features on CT.
目的:分析发生于眶骨的占位性病变的CT表现及其与组织病理学之间的关系。方法:回顾性收集15例经临床表现、影像学特征、病理证实为发生于眶骨占位病变患者的临床资料,分析其CT检查、组织病理学切片及其他临床表现。结果:在15例患者中,经病理诊断为骨瘤的患者有4例,骨内血管瘤3例,骨样骨瘤和骨化性纤维瘤各2例,嗜酸性肉芽肿3例,尤文肉瘤1例。骨瘤由成熟板层骨构成,对应在CT上呈现为高密度的骨样结节状隆起;骨内血管瘤病理主要表现为骨小梁间的畸形血管,在CT上表现为典型的“栅栏状”“蜂窝状”特征;骨样骨瘤以骨样组织和结缔组织为主,在CT上为类圆形的高密度影,中央为典型的低密度“瘤巢“影,外周为增生的骨密度影;骨化性纤维瘤由增生的纤维组织及骨样组织构成,CT表现为肿瘤表面常有骨壳包绕,病变多呈圆形或椭圆形;嗜酸性肉芽肿主要由大量朗格汉斯细胞组成,对应CT上的软组织肿块影,可伴溶骨性破坏;尤文肉瘤以低分化的小圆细胞为主,CT表现为虫蚀样骨质破坏,破坏的骨组织间有软组织病变。结论:发生于眶骨的各类病变有其特有的病理组成,不同的病理组成在CT上表现出相应的影像特征。
Objective: To analyze computed tomography (CT) manifestations of space-occupying lesions of the orbital bone and their relationship with histopathology. Methods: The clinical data of 15 patients with orbital bone occupying lesions confirmed by clinical manifestations , imaging features and pathological symptoms features were retrospectively collected, and their CT examination, histopathological sections and other clinical manifestations were analyzed. Results: Among the 15 patients, 4 cases were pathologically diagnosed with osteoma, 3 cases of intraosseous hemangioma, 2 cases of osteoid osteoma and 2 cases of ossifying fibroma, 3 cases of eosinophilic granuloma and 1 case of Ewing’s sarcoma. Osteoma was composed of mature lamellar bones, which corresponded to a high-density osteoid nodular protuberance on CT. The pathological features of intraosseous hemangioma were mainly malformed blood vessels between bone trabeculae and typical “fence” and “honeycomb” features on CT. Osteoid osteoma was mainly composed of bone-like tissue and connective tissue, mainly showing round high-density shadow, typical low-density “tumor nest” shadow in the center, and hypertrophic bone density shadow in the periphery. Ossifying fibroma was composed of proliferative fibrous tissue and bone-like tissue. CT showed that the surface of the tumor was often surrounded by bone shell, and the lesions were mostly round or oval. Eosinophilic granuloma was mainly composed of a large number of Langerhans cells, which corresponded to the soft tissue mass on CT and could be accompanied by osteolytic destruction. Ewing’s sarcoma was mainly composed of poorly differentiated small round cells, and CT manifestations were worm-eaten bone destruction with soft tissue lesions between destroyed bone tissues. Conclusion: Various lesions occurring in the orbital bone have their own special pathological composition. Different pathological components show corresponding imaging features on CT.