目的：设计一套瞳孔动、静态信息提取方案，尝试初步建立正常人群瞳孔动、静态信息数据库。方法：于2023年1月—7月，从中山大学眼科中心眼科门诊招募无眼部疾病、全身疾病的参与者。使用工业级红外相机搭配850 nm红外光源录制参与者瞳孔区域20 s视频，提取瞳孔横径数据并输出为txt文件。使用R语言分析数据，构建瞳孔舒缩过程中的波峰、波谷拟合线，并估算瞳孔舒缩频率。结果：共收集32位参与者的瞳孔动态数据，右眼数据纳入主要结果的分析。参与者年龄范围为7~61岁，男性占50%，等效球镜度范围为-5.630~+5.00 D。测量过程中的瞳孔横径平均值与年龄呈负相关，与等效球镜度、性别无关。在20 s的记录中，瞳孔舒缩次数为(15±7)次。基于波峰与波谷拟合线的趋势，瞳孔舒缩动态分为3种类型：舒缩扩张型、舒缩稳定型和舒缩缩小型。舒缩稳定型进一步分为稳定扩张型、稳定恒定型和稳定缩小型3个亚型，其中25人为舒缩缩小型。双眼的过滤后波峰、波谷拟合线的斜率和截距与过滤前比较差异无统计学意义(P>0.05)。结论：低成本、简易的设备配以算法可以便捷、快速地提取瞳孔动、静态信息。

Objective: To design a method for extracting dynamic and static information of the pupil and to establish a database of pupil dynamic and static information in a healthy population. Methods: From January to July 2023, subjects without any ocular or systemic diseases were recruited from the ophthalmology outpatient department. An industrial-grade infrared camera, paired with an 850nm infrared light source, was used to record 20-second videos of the pupil area of each subject. Horizontal pupil diameter data was extracted and saved as txt files. The data was analyzed using R software to construct fitted lines of peaks and troughs during the pupil constriction and dilation process, and the frequency of pupil contraction and dilation was estimated. Results: Pupil dynamic data was collected from 32 subjects with an age range of 7 to 61 years, of whom 50% were male. The spherical equivalent range was from +5.00 D to -5.625 D. The average number of pupil contractions and dilations within the 20-second recordings was (15 ± 7) cycles. Based on the trend of fitted lines for peaks and troughs, pupil dynamic types were categorized into three types: dilation type, stable type, and contraction type. The stable type was further divided into stable dilation, stable constant, and stable contraction subtypes. 25 subjects exhibiting the constriction type. A paired t-test showed no significant difference in the slope and intercept of the fitted lines for peaks and troughs between both eyes. Conclusion: Low-cost and simple equipment combined with algorithms can efficiently and quickly extract dynamic and static pupil information.

目的：探讨伴无前房、白内障的葡萄膜炎继发性青光眼的手术治疗方法。

方法：采用经角膜缘的晶状体和前段玻璃体切除或经睫状体平坦部的晶状体和玻璃体切除联合小梁切除术，对7只眼伴有无前房、白内障的葡萄膜炎继发性青光眼进行了手术治疗，观察术前术后眼压和前房深度变化、滤过泡、视力以及并发症情况，随访时间3～48个月。

结果：(1)眼压：7只眼术前平均眼压为(5.18±0.77)kPa，术后1天平均眼压为(0.95±0.29)kPa，术后1周平均眼压为(0.93±0.12)kPa，最后1次随访平均眼压为(1.14 4-0.70)kPa；(2)前房深度：所有患眼术后均形成前房，中央前房深度为3～5CT；(3)滤过泡情况：所有患眼术后均形成功能滤过泡，滤过泡形态为扁平弥散；(4)视力：1患眼术前视力0.01，术后1周视力CF／20am，最后1次随访矫正视力0.06；1患眼术前视力0.05，术后1周0.01，最后1次随访矫正视力0.1；余患者多为幼儿，不能配合视力检查但可追光；(5)术后并发症：所有患眼术后早期均有角膜水肿，瞳孔区均有纤维性渗出，房水闪辉(+～++++)，但均未出现瞳孔和周切口膜闭、视网膜脱离和眼内炎等并发症。

结论：对于葡萄膜炎继发性青光眼同时伴无前房或极浅前房、白内障玻璃体混浊患者，晶状体玻璃体切除联合小梁切除手术能有效降低眼压，形成前房，无严重并发症，是一种治疗伴无前房的葡萄膜炎继发性青光眼安全有效的方法。

Purpose：To evaluate the efficacy of combined trabeculectomy，lensectomy and vitreeto—my for the management of secondary glaucoma in uveitis with extremely shallow anterior chamber and cataract.

Methods: Combined trabeculectomy, lensectomy and vitrectomy were undertaken formedically uncontrolled intraocular pressure (IOP)on 7 eyes (6 patients, aged from 4months to 20 years) with secondary glaucoma in uveitis in a retrospective cohort studybetween 2001 and 2005.

Resuls : The follow-up period ranged from 3 months to 4 years. Deep anterior chamberand functional bleb were observed in all the eyes postoperatively. The average IOP preoperatively, one day postoperatively, one week postoperatively, and the last time of fol-low-up were(5.18±0.77)kPa,(0.95 +0.29)kPa,(0.93 +0.12)kPa, and(1.14±0, 70 ) kPa respectively. No severe complication was observed postoperatively exceptfor the corneal edema and fber exudation.
Conclusions : Combined trabeculectomy, lensectomy and vitrectomy serve as effectiveand safety treatments for secondary glaucomous uveitis accompanied by extremely shal-low anterior chamber, cataract and vitreous opacity. Further intriguing study comparingthis combined surgery with combined phacoemulsification and drainage implant surgeryis warranted.