一名36岁的女性于16年前因静脉滴注“青霉素”引发Stevens-Johnson综合征，出现皮肤剥脱，口、鼻腔黏膜破损出血，双眼红肿伴分泌物增多等症状，当时经过治疗症状基本缓解。数月后开始反复出现眼部不适，2010年患者的视力明显下降，眼部疼痛加重，伴畏光流泪。至2016年入暨南大学附属第一医院时双眼最佳矫正视力仅0.1(右眼)、光感(左眼)，双眼角膜混浊，新生血管长入，甚至出现睑球粘连。80%的SJS患者可伴有眼部并发症，经过治疗症状缓解后，眼部病变仍可能继续进展，最终导致视力障碍甚至更严重的后遗症。因此患者病情稳定后仍须随诊，密切关注眼部、皮肤及黏膜的变化情况。

A 36-year-old woman developed Stevens-Johnson syndrome 16 years ago due to intravenous infusion of “penicillin”. She developed symptoms such as skin exfoliation, oral and nasal mucous damage, redness and swelling of the eyes, and increased secretions. TTe condition was relieved affer treatment. A few months later she repeated eye discomfort, in 2010 the patient’s visual acuity decreased significantly, eye pain increased with photophobia and tears. Her best-corrected visual acuity (BCVA) was only 0.1 for the right eye and light perception for the left eye, corneal opacity, angiogenesis, and even the symblepharon were observed when admitted to First Affiliated Hospital of Jinan University in 2016. About 80% of Stevens-Johnson syndrome patients may be accompanied by ocular complications. Although the ocular symptoms are relieved after treatment, eye disease is still likely to progress, eventually leading to visual impairment and even more serious sequelae. TTerefore, patients with stable condition still need follow-up, and close attention should be paid to the changes of the eyes, skin and mucous membranes.