Background: Ophthalmology is an important medical science subject, but it is given with insufficient
attention in undergraduate medical education. Flipped classroom (FC) and problem-based learning (PBL)
are well-known education methods that can be integrated into ophthalmology education to improve students'
competence level and promote active learning.
Methods: We used a mixed teaching methodology that integrated a FC and PBL into a 1-week
ophthalmology clerkship for 72 fourth-year medical students. The course includes two major sessions: FC
session and PBL session, relying on clinical and real-patient cases. Written examinations were set up to assess
students’ academic performance and questionnaires were designed to evaluate their perceptions.
Results: The post-course examination results were higher than the pre-course results, and many students
gained ophthalmic knowledge and learning skills to varying levels. Comparison of pre- and post-course
questionnaires indicated that interests in ophthalmology increased and more students expressed desires to be
eye doctors. Most students were satisffed with the new method, while some suggested the process should be
slower and the communication with their teacher needed to strengthen.
Conclusions: FC and PBL are complementary methodologies. Utilizing the mixed teaching meth of FC
and PBL was successful in enhancing academic performance, student satisfactions and promoting active
learning.