目的：探讨3种不同的滴眼液在麻醉小鼠晶状体浑浊中的保护作用。方法：将20只6周龄C57BL/6j小鼠分为4组，A组为自然暴露组(对照组)，B组为滴用透明质酸钠组，C组为滴用甲基纤维素滴眼液组，D组为滴用生理盐水组。分别于麻醉后10，20，30，45和60 min观察小鼠晶状体浑浊情况。结果：与A组相比，3种滴眼液均不同程度地延长小鼠晶状体浑浊的时间；30 min时，4组小鼠浑浊 发生率分别为90%，50%，50%和10%，并延缓晶状体浑浊的进展；60 min时，4组小鼠3级浑浊的发生率为30%，10%，10%和0，其中生理盐水的作用效果最优，可以明显延迟晶状体变浑浊的时间。结论：麻醉小鼠的晶状体浑浊程度可以被相关滴眼液延缓，适用于短时间的眼科检查和处理，又因其经济易得，可广泛应用于小鼠活体的眼科检查中。
Objective: To study the effect of saline, carboxymethylcellulose sodium eye drops and sodium hyaluronate gel to stop the development of cataract in anesthetized mice. Methods: Twenty C57BL/6j mice, aged 6 weeks, were divided into four groups, group A was naturally exposed to air, group B was treated with sodium hyaluronate gel, group C was treated with carboxymethylcellulose sodium eye drops and group D was treated with saline. The lens opacity was observed at 10, 20, 30, 45 and 60 min after the start of the experiment. Results: Compared with group A, the eye drops delayed the development of lens opacity in varying degrees. At 30 min, the incidence rate of cataract in group A, B, C and D was 90%, 50%, 50% and 10%, respectively. At 60 min, the incidence rate of grade 3 cataract in group A, B, C and D was 30%, 10%, 10% and 0 respectively, saline did the best, which can significantly slow the process. Conclusion: Cataract development can be slowed by the protective eye drops. This finding is relevant for those experimental settings in which clear ocular media are required.
目的：探讨爱先蓝(Alcian Blue，AB)和细胞角蛋白(cytokeratin，CK)双重染色技术在泪腺腺样囊性癌组织中的应用, 提高泪腺腺样囊性癌染色效率。方法：选取中山大学中山眼科中心临床病理科2015年1月至2017年1月期间诊断为泪腺腺样囊性癌病例标本23例，在同一张切片上先进行AB染色，再进行CK染色，观察染色效果。结果：23例泪腺腺样囊性癌标本组织中黏液物质全部呈蓝色；癌细胞胞质CK阳性，呈棕黄色。结论：AB和CK双重染色方法稳定，颜色对比鲜明，能够良好显示癌细胞及黏液的关系，并且比分开的两次单种染色省时、经济。
Objective: To investigate the application of Alcian Blue (AB) and cytokeratin (CK) double staining technique in adenoid cystic carcinoma to improve the staining efficiency. Methods: Twenty-three specimens of adenoid cystic carcinoma from January 2015 to January 2017 in the Clinical Pathology Department of Zhongshan Ophthalmic Center, Sun Yat-sen University were stained with AB first and CK then on the same slide. Results: Mucinous substance showed blue. And the cytoplasm of the cancer cells presented with brown yellow in all the specimens.Conclusion: The method of double staining with AB and CK is stable and displays bright color contrast. It can effectively reveal the relationship between the mucus and cancer cells. It proves to be more time-saving and economical than the individual staining of AB and CK respectively.
目的：分析临床路径下青光眼住院费用变化情况，为制定合理的临床管理方法提供参考。方法：收集青光眼临床路径患者数据，建立 Excel 数据库，以 2016 年为基准对住院费用进行贴现计算后，应用 SPSS 软件对住院数据进行统计分析。结果：手术费用占总费用的比例最大，人均住院费用变化不明显，诊疗费逐年上升。随着日间手术的开展，实施临床路径管理的患者数量下降。结论：诊疗费用对提高医务人员工作积极性具有很重要的意义，随着日间手术的推广，将对临床路径的实施产生影响。
Objective: To investigate hospitalization costs through the inpatient costs of primary acute angle closure glaucoma between 2009 to 2016, and to provide a more suitable method for clinical management.
Methods: We collected the data of hospitalization patients with glaucoma from 2009 to 2016, coded and established the corresponding Excel databases. Based on a variety of statistics tables, descriptive analysis (according to SPSS for Windows 17.0) was applied to analyze the proportion of different types of hospitalization costs and simple linear regression was used to analyze the tendency of costs with years.
Results: Operation costs was the largest percentage of total cost; the average hospitalization cost change was not obvious, and the treatment costs rose year by year. With the development of day surgery, patients of clinical pathway management was decreased.
Conclusion: Increasing the medical expenses to improve medical staff’s work enthusiasm has very important significance. As day surgery, will affect the implementation of clinical pathway.
随着亚太眼科学会(Asia-Pacific Academy of Ophthalmology，APAO)永久会址和秘书处落户在中山大学中山眼科中心珠江新城院区眼科学国家重点实验室大楼(中国广州)，在大数据时代背景下，建设先进的亚太级眼科学科学数据中心已成为亚太眼科创新战略发展的需要。通过建设科学数据中心，一方面缓解眼科学国家重点实验室项目科研数据增长压力，一方面为眼科大数据与人工智能等新兴科研项目开展提供保障平台，为亚太眼科学科建设打下坚实的数据基础。科学数据中心设计建设遵照国家《科学数据管理办法》实施，以加强和规范科学数据管理，保障科学数据安全，提高开放共享水平，更好支撑国家科技创新、经济社会发展和符合国家信息安全建设方针。
As the Asia-Pacific Academy of Ophthalmology (APAO) secretariat permanently located in the building of State Key Laboratory of Ophthalmology (Guangzhou, China). In big data time, it’s a problem for the development of the Asia-pacific ophthalmology innovation strategy to construct the Asia-pacific science data center of ophthalmology. Through the construction of science data center, alleviate the pressure of the state key laboratory of ophthalmology data growth, for big data and new research fields such as artificial intelligence to provide guarantee, provided a basis for the Asia-pacific eye subject construction. Science data center construction in accordance with national “scientific data management method”, to strengthen and standardize the scientific data management, to ensure the safety of scientific data, improve the level of open sharing, better support scientific and technological innovation, economic and social development and national security as a policy.
