专家访谈
论著

汕头地区城乡中小学生双眼水平融合力的横断面调查

Cross-sectional study of youth fusional range among school children in Shantou District

:100-104
 
目的:通过三棱镜融合储备力试验检查了解正常青少年的双眼水平融像性聚散范围。方法:横断面研究,随机分层整群抽样调查。在汕头地区调查9所城乡中小学校,共7 537人。从体检学生中抽取双眼正常学生4 012名,用排状三棱镜检查双眼近距水平聚散力,在融像破裂点记录三棱镜度数。按集合与散开、年龄、性别等因素对结果作分层统计分析。结果:总体检人数7 464人,其中双眼祼眼视力≥0.8为4 012人,占体检人数的53.75%;研究对象的双眼散开运动范围平均为15.87△±10.74△,双眼集合运动范围平均为26.41△±12.04△;4~8岁组及9~11岁组的双眼集合与散开运动范围均高于12~20岁组,差异有统计学意义(P<0.05);女性的双眼集合能力高于男性。结论:在本调查人群中,双眼集合运动的储备力高于散开运动;年龄越小,双眼异向运动的储备力越强。
Objective: To investigate the fusional range by using prism bar among students in Shantou City of Guangdong Province, China. Methods: This was a cross-sectional study that included 4 012 normal eye subjects among randomly selected 7 537 students aged 6 to 19 years from 9 schools in Shantou City. Horizontal fusional range measured with prism bar. Statistical analyses were performed using SPSS statistical software to investigate the association of age, gender, vergence and divergence. Results: A total of 7 464 students were examined, including 3 928 boys and 3 536 girls, mean age 11 years. The number of students with binocular vision ≥0.8 was 4 012, accounting for 53.75% of the number of fusional examination; the mean vergence range was 15.87△±10.74△, and the mean divergence range was 26.41△±12.04△. The vergence and divergence range group of 4 to 8 years and 9 to  11 years students was higher than the group of 12 to 20 years, the difference was statistically significant (P<0.05). The vergence range of female students was higher than that of male students. Conclusion: In this study, the vergence range is higher than divergence. With an increase in ages, the range of vergence and divergence decreases.
论著

像差和对比敏感度数据提取处理软件的开发和应用

Development and application of aberration and contrast sensitivity data extraction software

:95-99
 
目的:像差和对比敏感度检查结果数据繁多复杂。为了高效准确地完成检查数据提取工作,自主开发一款像差和对比敏感度数据提取处理软件(Aberrations and Contrast Sensitivity Helper,ACSH)。方法:参考其他同类软件的设计模式,结合我院科研实际,采用开发工具VB6.0编程实现。结果:ACSH在Windows的运行环境下,能够准确地在局域网环境下实现对iTrace,Zywave像差仪和Optec_6500对比敏感度测试仪的检查数据进行提取。像差仪信息包括病人基本信息、屈光度、眼别、瞳孔直径,各项像差Zernike系数,高阶像差和总高阶像差均方根RMS(Root Mean Square)。对比敏感度仪数据包括:病人基本信息、检查时间、检查时的模拟光照度和眩光强度、 各空间频率的对比敏感度数值。同时软件支持对已提取的数据进行浏览、查询及导出EXCEL等功能,并开放数据接口供电子病历等其他系统对接。结论:ACSH是一款能够有效辅助视光专科科研和临床工作的应用软件。
Objective: Aberration and contrast sensitivity test results data is various and complex. In order to complete efficiently and accurately the data extraction work, we developed an aberration and contrast sensitivity data extraction software Aberrations and Contrast Sensitivity Helper (ACSH). Methods: VB6.0 was used as a development tool after we referred to other similar software design pattern and combined the reality of our scientific research. Results: The ACSH under the Windows environment can accurately extract the results’ data of iTrace and Zywave aberration meter and Optec 6500 contrast sensitivity tester in local area network. Aberration instrument information include patients’ basic information, refraction, which eye, pupil diameter, the aberration  Zernike coefficients, the high-order aberration and total aberration Root Mean Square (RMS). Contrast sensitivity tester data included: patients’ basic information, time, the intensity of analog light and the glare ,the contrast sensitivity values of every spatial frequency. ACSH is able to browse and query extracted data and export to EXCEL, and open data interface for electronic medical records and other system. Conclusion: ACSH is an effective software which assists optical specialized scientific research and clinical work.
论著

感染性角膜炎的隔离管理

Isolation and management of infectious keratitis

:88-90
 
目的:规范感染性角膜炎的隔离管理。方法:回顾性分析感染性角膜炎患者在住院期间发生交叉感染的危险因素,探讨现行的隔离管理措施是否有效。结果:隔离管理到位,5年的院感发生率为0.08%。结论:规范感染性角膜炎的隔离管理,能有效地预防医院感染。
Objective: To standardized the isolation and management of infectious keratitis. Methods: Risk factors of cross-infection of patients with infectious keratitis during their hospitalization were retrospectively reviewed to investigate whether the current isolation management is effective. Results: The current isolation management is effective since the incidence of hospital infection was 0.08% in past 5 years. Conclusion: Standardized the isolation management of infectious keratitis can prevent hospital infection efficaciously. 
论著

不同病变阶段视网膜色素变性患者脉络膜血管状态的荧光血管造影特征

Characters of choroid in different stages of retinitis pigmentosa

:74-79
 
目的:探讨不同病变阶段视网膜色素变性患者的脉络膜血管状态。方法:回顾性分析云南省第二人民医院眼科2000年1月至2015年4月诊断为原发性视网膜色素变性的患者226例(452眼)的眼底特征,并复习相关文献,重点分析总结脉络膜血管情况。结果:31例(62眼)病变前期患者,荧光素眼底血管造影显示动脉期脉络膜血管及视网膜血管充盈正常,未出现充盈延迟或缺损现象。25例(50眼)病变早期患者,荧光素眼底血管造影显示动脉前期可见脉络膜背景荧光显示,部分脉络膜毛细血管未同时充盈,动脉期时上述部分完成充盈。106例(112眼)病变中期患者,荧光素眼底血管造影显示动脉期出现部分脉络膜毛细血管萎缩区,仅能看到残存的粗大脉络膜血管,随造影过程的进展,此区域并未出现充盈,即呈现永久的脉络膜毛细血管充盈缺损。64例(128眼)病变晚 期患者荧光素眼底血管造影显示,广泛的脉络膜毛细血管萎缩区,其间可见残存的脉络膜粗大血管,至造影晚期均呈现充盈缺损,萎缩区边缘随造影过程呈强荧光表现。结论:荧光素眼底血管造影可显示脉络膜血管萎缩变化情况,这一指标可作为反映不同病变阶段视网膜色素变性患者病情进展变化的重要依据。
Objective: To investigate clinical characteristics of choroid in different stages of retinitis pigmentosa. Methods: The characteristics of fundus, visual conditions and characters of choroid of 226 cases (452 eyes) patients with retinitis pigmentosa in No. 2 People’s Hospital of Yunnan Province from Jan.2000 to Apr.2015 were retrospectively analyzed. Results: Fundus fluorescein angiography of 31 cases (62 eyes) before early stage showed:  arterial choroidal and retinal vascular filling normal, filling delay or defect phenomenon does not be observed. Fundus fluorescein angiography 25 cases (50 eyes) patients in early disease showed: preliminary choroidal artery background fluorescence was displayed, at the same time, part of the choriocapillaris was not filling, the filling was completed in arterial stage. Fundus fluorescein angiography of 106 cases (112 eyes) patients in the medium-stage showed: arterial phase appears part choriocapillaris atrophy area, thick choroidal vessels can be seen, with the progress angiography procedure, filling was not be observed in this area, which presents permanent choriocapillaris filling defect. Fluorescein angiography of 64 cases (128 eyes) in patients in advanced stage showed widespread choriocapillaris atrophy area, during which thick choroidal vessels remaining filling defect in late stage, atrophic area with a contrast edge high fluorescence performance. Conclusion: Fluorescein angiography can show choroidal atrophy changes, it can be used as an indicator to assess the progression of retinal changes in patients with retinitis pigmentosa.
论著

表面切削手术前后角膜光密度变化的研究及术后Haze数据库的初步建立

Corneal density after surface ablation and the establishment of preliminary Haze database

:68-73
 
目的:了解表面切削手术前后角膜透明性变化,初步建立角膜光密度与角膜上皮下雾状混浊(Haze)对应的数据库。方法:收集我院行表面切削手术的病人74人146眼。患者手术前、术后3个月行裂隙灯角膜透明性检查和眼前节分析仪(Pentacam,0表示角膜完全透光,100表示角膜混浊不透光)测量角膜光密度。使用SPSS13.0软件对数据进行统计,术前、术后3个月角膜光密度进行Wilcoxon秩和检验;根据裂隙灯下角膜透明性将术后数据分成透明角膜组和Haze组与术前分别对比。术后角膜光密度与裂隙灯下Haze分级进行等级资料Spearman相关分析;按照裂隙灯分级将不同程度Haze与角膜光密度对应,初步建立术后Haze的角膜光密度数据库。结果:术后3个月时,透明角膜(0级Haze)80眼、I级Haze49眼、II级Haze 13眼、III级Haze2 眼、IV级Haze2眼。术前最大 角膜光密度平均值为19.7±2.47,术后3个月时最大角膜光密度平均值为30.3±7.2,术后角膜光密度比术前升高(Z=?7.404,P<0.001);另外术后Haze组和术后透明角膜组光密度分别为38.2±15.2和21.2±3.51,与术前比两者差异也有统计学意义(Z=?4.783,P<0.001;Z=?5.195,P<0.001)。术后角膜光密度与Haze呈正相关(r=0.819,P<0.001)。各级Haze组对应角膜光密度参考值为I级Haze:29.4±2.58;II级Haze 43.2±5.68;III级Haze:59.5±0.92;IV级Haze: 89.5±14.9。结论:Haze的出现使光密度增加,影响角膜的透明性。手术后裂隙灯观察下的透明角膜光密度较术前高,可能与术后角膜的炎症反应或胶原纤维排列变化有关,需要进一步研究明确。表面切削手术前后角膜的透明性除了传统的裂隙灯检查外,也可以用角膜光密度来评价。用角膜光密度来评价角膜的透明性比单纯的裂隙灯检查更容易发现细微的异常。
Objective: To measure corneal transparency before and after the surface ablation and establish a preliminary database of corneal density and haze. Methods: Seventy-four patients (146 eyes) who underwent surface ablation were measured with the slit lamp and the densitometry program of the Pentacam Scheimpflug imaging system (0=no clouding, 100=tissue completely opaque). The corneal density before and after operation were analyzed with the Wilcoxon’s Matched Pairs Test of the SPSS 13.0. Eyes of 3 months after operation were categorized as postoperative clear corneas and postoperative with haze. According to the slit lamp, different degrees of haze were correlated with corneal density to establish a preliminary corneal density database.Results: At 3 months after operation, there were 80 eyes with clear cornea (grade 0 haze) and 66 eyes with haze which contained 49 eyes with grade I haze, 13 eyes with grade II haze, 2 eyes with grade III haze and 2 eyes with grade IV haze. Maximum density of preoperative corneas was 19.7±2.47, and it was increased to 30.3±7.2 postoperation (Z=?7.404, P<0.001). Maximum density of postoperative clear corneal (21.2±3.51) and postoperative with haze (38.2±15.2) were both higher than preoperation (Z=?5.195, P=0.004 and Z=?4.783, P<0.001). And the haze correlated corneal density was grade I haze 29.4±2.58; grade II Haze 43.2±5.68; grade III haze 59.5±0.92; grade IV haze 89.5±14.9. Conclusion: Corneal density will increase with haze. Maximum density of postoperative clear corneal was higher than preoperation which may be influenced by the postoperative corneal inflammation or the rearrange of collagen ,and it need the further research. Besides the slit lamp, we can use the corneal density to measure the corneal transparency after surface ablation. The densitometry program of the Pentacam can provide a useful objective measure of postoperative and other mild corneal haze.
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  • 眼科学报

    主管:中华人民共和国教育部
    主办:中山大学
    承办:中山大学中山眼科中心
    主编:林浩添
    主管:中华人民共和国教育部
    主办:中山大学
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  • Eye Science

    主管:中华人民共和国教育部
    主办:中山大学
    承办:中山大学中山眼科中心
    主编:林浩添
    主管:中华人民共和国教育部
    主办:中山大学
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