高度近视合并白内障患者术后有效晶状体位置的初步临床研究

Clinical study of effective lens position after cataract surgery in high myopia eyes

:136-140
 

目的:探讨高度近视合并白内障患者白内障术后有效晶状体位置的变化。方法:收集白内障超声乳化摘除联合人工晶状体植入术的高度近视合并白内障患者 21 例共 27 眼,记录术后 1 d、1 周、1 个月视力、屈光度、有效晶状体位置。结果:高度近视合并白内障患者术后 1 d、1 周、1 个月有效晶状体位置分别为(4.17±0.39),(4.09±0.38),(4.31±0.44) mm,且组间比较差异有统计学意义(P < 0.05)。有效晶状体位置的实际轴向运动为(0.19±0.13) mm,与晶状体厚度呈正相关(r = 0.648,P < 0.001),与术前眼轴无相关关系(r = 0.227,P = 0.255)。结论:高度近视合并白内障患者术后 1 d 至 1 周人工晶状体轻度前移而造成近视偏移,而术后 1 个月时则呈远视偏移,且术后有效晶状体位置位移与术前晶状体厚度相关。


Objective: To investigate the change and influencing factors of the effective lens position after cataract surgery in high myopia eyes. Methods: We collected 27 eyes of 21 patients with high myopia who underwent phacoemulsification and intraocular lens implantation. The visual acuity, diopter and effective lens position were recorded 1 day, 1 week, and 1 month after operation. Results: The effective lens position of high myopia combined with cataract patients at 1 day, 1 week, and 1 month was (4.17±0.39), (4.09±0.38), and (4.31±0.44) mm, respectively. The effective lens positions significantly differed between the groups after surgery (< 0.05). The ELPRMS was (0.19±0.13) mm. The ELPRMS was positively correlated with the lens thickness (0.648, < 0.001),whereas was not correlated with the preoperative axial length (r 0.227, P = 0.255). Conclusion: High myopic patients with cataract have a slight forward movement of the effective lens position from 1 day to 1 week after surgery, and a hyperopic shift from 1 week to 1 month. The displacement of effective lens position after surgery is correlated with the preoperative lens thickness.

论著

超广角眼底成像在近视患者周边视网膜病变的临床应用

Clinical application of ultra-wide field laser ophthalmoscope in peripheral retinopathy in myopic patients

:130-135
 

目的:评价欧堡 Daytona 200 度超广角激光扫描检眼镜检查近视患者眼底周边部视网膜病变的应用价值。方法:本研究为前瞻性病例研究,收集爱尔眼科医院要求行屈光手术的近视患者 1 000 例(2 000 只眼),分别进行小瞳下欧堡 Daytona 200 度超广角激光扫描检眼镜眼底检查和散瞳后三面镜检查,记录检查结果并进行比较分析。结果:通过欧堡 Daytona 200 度超广角激光扫描检眼镜检查发现有周边视网膜病变共 230 例(310 只眼),检出阳性率为 15.50%;三面镜检查发现周边部视网膜病变共 242 例(322 只眼),检出阳性率为 16.10%。两种检查方法对近视患者周边部视网膜病变检出阳性率具有很好的一致性(Kappa 值 0.8~1.0)。结论:欧堡 Daytona 200 度超广角成像系统为检查周边部视网膜病变提供了更省时高效的方法,在屈光手术前筛查视网膜周边部病变,具有广阔的临床应用前景。

Objectives: To evaluate the clinical value of peripheral retinal diseases in myopic patients examined by 200-degree ultra-wide field laser ophthalmoscope (Daytona). Methods: This was a prospective case-control study. We collected 1 000 myopic patients (2 000 eyes) who were scheduled to undergo refractive surgery in Aier Eye Hospital. They were examined by 200-degree ultra-wide field laser ophthalmoscope (Daytona) with non-mydriasis and three-mirror contact lens with mydriasis. The examination results were recorded and statistically analyzed. Results: A total of 230 cases (310 eyes) with peripheral retinopathy were found by 200-degree ultra-wide field laser ophthalmoscope (Daytona). The positive rate was 15.50%; 242 cases (322 eyes) with peripheral retinopathy were found by threemirror contact lens, and the positive rate was 16.10%. The two methods were consistent in the detection of peripheral Retinopathy in myopic patients (the Kappa value is between 0.8 and 1.0). Conclusion: 200-degree ultra-wide field laser ophthalmoscope (Daytona) is an effective and rapid method for detecting peripheral retinopathy. It provides a broad clinical application prospects for peripheral retinopathy screening before refractive surgery. 

封面故事
医学教育

以上睑下垂为例阐明教学查房在外眼疾病教学中的重要性

Importance of teaching rounds in the teaching of external eye diseases illustrated by taking blepharoptosis as an example

:126-128
 

教学查房是手把手教学的重要手段和具体表现,是让同学们把书本知识应用到医疗诊疗中的重要桥梁。眼科学具有形象生动、结构复杂、直观性和操作性强等特点。外眼疾病的特征更是显而易见,针对外眼疾病诊疗中的一些不规范的操作也更易暴露出来。本文以上睑下垂为例,旨在阐明教学查房在外眼疾病教学中的重要性。

Teaching rounds are an important means and concrete manifestation of hands-on teaching, and an important bridge for students to apply book knowledge to medical diagnosis and treatment. Ophthalmology has the characteristics of vivid image, complex structure, intuition and strong operability. The characteristics of external eye diseases are more obvious, and some non-standard operations in the diagnosis and treatment of external eye diseases are easier to expose. This article takes blepharoptosis as an example to illustrate the importance of teaching rounds in the teaching of external eye diseases.

后极部中心性脉络膜营养不良 2 例

Posterior polar central choroidal dystrophy: 2 cases report

:120-125
 

后极部中心性脉络膜营养不良是一种罕见疾病。本文对 2 例患者进行了荧光素眼底血管造影、眼底自发荧光、相干光层析成像及视觉电生理等检查。眼底检查可见双侧后极部血管弓范围视网膜色素上皮(retinal pigment epitheliumRPE)及脉络膜毛细血管的对称性萎缩。自发荧光可见相应区域的对称性低荧光。光学相干断层成像术(optical coherence tomographyOCT)显示后极部外层视网膜和脉络膜毛细血管的萎缩变薄。

Posterior polar central choroidal dystrophy is a rare disease. Clinical data of two patients with posterior polar central choroidal dystrophy fluorescein angiography, fundus autofluorescence (FAF) imaging, optical coherence tomography (OCT), and electrophysiological tests were reported. Fundus examination showed bilateral symmetric atrophy of the retinal pigment epithelium and choriocapillaris in the posterior polar areas between vascular arcades. FAF imaging showed clearly defined hypoautofluorescent areas that corresponded to the aforementioned lesions. Atrophy of the choriocapillaris and outer retinal layer were detected by optical coherence tomography.

临床病例讨论

新发双侧强直性瞳孔1例

Newly bilateral tonic pupil: A case report

:116-119
 

强直性瞳孔在临床工作中较为少见,容易被误诊,典型的强直性瞳孔为单侧,随着病程的进展,逐渐转变为双侧。新发双侧强直性瞳孔更是极为罕见,应当引起重视。其典型的临床表现包括瞳孔散大、瞳孔运动迟钝、节段性瞳孔麻痹、无其他眼部器质性病变。依据病因可以分为继发于急性眼内肌麻痹、合并有全身疾病以及特发性三类。目前治疗方面多以病因治疗为主。

Tonic pupil is rare in clinical work and likely to be misdiagnosed. The typical tonic pupil is unilateral, which gradually turns to bilateral with the progress of disease. Newly bilateral tonic pupil is extremely rare, which captivates widespread attention. Typical clinical manifestations include dilated pupils, slow pupil movement, segmental pupillary palsy, and no other ocular diseases. On this basis, the causes can be divided into three categories, including secondary to acute intraocular myoparalysis, complicated with systemic disease and idiopathic type. At present, etiological treatment is the main treatment.

门急诊与住院病房一体化管理模式下眼外伤急诊手术患者的护理

Nursing methods for ocular traumatic patients in the integrated management mode of ocular trauma emergency room and ward

:112-115
 

目的:探讨眼外伤门急诊与住院病房一体化管理模式下,眼外伤患者的护理方法。方法:2018年4月中山大学中山眼科中心 109 例眼外伤急诊手术患者采取有效的护理措施,通过交谈、示范、发放宣传资料等方法,对患者实施心理护理、术前护理、术后护理、出院指导及延续护理。果:109 例患者均顺利接受手术,其中门急诊患者 43 例当天行手术治疗并于第 2 天眼外伤急诊专科门诊复诊,收入院患者 66 例行手术治疗均治愈出院。结论:在门急诊与住院病房一体化的管理模式下,对患者做好心理护理、术前术后护理及出院指导,使患者安心接受手术,得到相应的健康指导,提高了患者的满意度,值得推广。

Objective: To explore the nursing methods for ocular traumatic patients in the integrated management mode of ocular trauma emergency room and ward. Methods: We took effective nursing measures for the patients who treated with surgeries in our ocular traumatic emergency room, including comprehensive conversation, demonstration, distribution of detailed propaganda, discharge guidance as well as preoperative, postoperative, and discharge psychological nursing, from 1st April, to 30th April, 2018. Results: A total of 109 patients were included in this study. Forty-three of them underwent the emergency surgery on the day of admission and reviewed in the outpatient at postoperative 2 days. The other 66 patients were hospitalized, recovered and discharged. Conclusion: In this integrated management mode, comprehensive psychological nursing, perioperative nursing and discharged guidance would help to comfort patient and improve the degree of satisfaction, which is worthy of widespread application.

眼科护理

以护士为主导的按术式排程手术日模式在眼整形病区的实施与成效

Implementation and effect of the mode of nurse-led surgery scheduling based on procedure in ocular plastic ward

:108-111
 

目的:探讨以护士为主导的按术式排程手术日模式在眼整形病区的应用与成效。方法:采用便利抽样法,选择实施以护士为主导的按术式排程手术日模式后的 2018年1至6月作为试验组,实施该模式前的 2017年1至6月作为对照组。统计并比较该模式实施前后平均每周手术量、病区关闭时长、水电费用、医务人员对工作的满意度及患者的满意度。结果:该模式实施后平均每周的手术台数由实施前的 26 台升至 31.8 台,关区时长由实施前的 4.5 h 升至 33.2 h,水电费由实施前的 625.3 元降至 518.5 元,差异有统计学意义(t2.61,3.94,4.22,P < 0.05);医护人员对工作的满意度由实施前的 80% 上升至 90%,患者满意度由实施前的 83.3% 上升至 93.3%,差异有统计学意义(χ24.61,5.01,P < 0.05)。结论:以护士为主导的按术式排程手术日模式在眼整形病区切实可行,在保障医疗、护理安全性的同时,可节省医院的运营成本,亦可提高护士、医生、患者的满意度,值得在临床推广。

Objective: To explore the effect of the mode of nurse-led surgery scheduling based on procedure in ocular plastic ward. Methods: Convenience sampling method was adopted, the nurse-led surgery performed from January to June 2018 was assigned in the experimental group, and those conducted from January to June 2017 were assigned into the control group. The average number of operations per week, the length of the ward closure, utilities, medical staff and patients' satisfaction were calculated and compared. Results: After the implementation of this mode, the average number of operations per week increased, the length of the ward closure increased, utilitiesdecreased, and the difference was statistically significant (t=2.61, 3.94, 4.22, P<0.05). The degree of satisfaction of medical staff and patients was significantly improved (χ2=4.61, 5.01, P<0.05). Conclusion: The mode of nurse-led surgery scheduling based on procedure can save hospital operating costs and improve the satisfaction of nurses, doctors and patients, which is worthy of clinical promotion.

四川地区脉络膜黑色素瘤患者GNAQ,GNA11基因突变检测

Genetic analyses of GNAQ and GNA11 mutation in uveal melanoma in Sichuan

:99-102
 

目的:检测四川地区脉络膜黑色素瘤患者GNAQGNA11基因的突变情况。方法: 22 名脉络膜黑色素瘤患者行眼球剜除术,眼球组织用甲醛固定,石蜡包埋保存。从肿瘤石蜡切片中提取 DNA 进行 PCR 扩增反应,并对 GNAQGNA11 突变位点进行测序分析。结果: 16 名患者的肿瘤组织中检测到 GNAQ  GNA11 基因突变,总突变率为 72.73%,其中 GNAQ 突变率为 45.45%,GNA11 突变率为 27.28%。结论:GNAQGNA11 基因在四川地区脉络膜黑色素瘤患者中的突变率较高。

Objective: To sequence the GNAQ and GNA11 mutation in patients with uveal melanoma from Sichuan Province. Methods: A total of 22 samples were collected from uveal melanoma patients. DNA was extracted from formalin-fixed paraffin-embedded tissue. Primers of GNAQ and GNA11 were synthesized. Polymerase chain reaction was performed and the products were sent to sequencing. Results: A total of 16 cases among the patients with uveal melanoma were found with GNAQ or GNA11 mutation. The overall mutation rate was 72.73%. And the mutation rates for GNAQ and GNA11 were 45.45% and 27.28%, respectively. Conclusion: The patients with uveal melanoma in Sichuan province have a high level of GNAQ /GNA11 mutation rate.


散光对使用 C 字视力表与 E 字视力表检测视力的影响

Influence of astigmatism on visual acuity by using C-type and E-type visual acuity charts

:103-107
 

目的:比较学生在不同散光欠矫下使用C字视力表和E字视力表所测的视力差别并分析其原因。

方法:选取 30 名 15~18 岁的学生,在完全矫正屈光度 MPMVA(maximum plus to maximum visual acuity)状态下,附加相应不同散光轴向的柱镜造成相应的散光度数后,比较使用两种不同的视力表测出的视力值。同时根据两种视力表不同的设计原理及记录方法,分析造成数值差异的可能原因。
结果: E 字视力表组相比,C 字视力表组附加各个轴向 +0.25 DC 柱镜组测得视力值均值差异较小,附加 +0.50 DC 差异较大,其中斜轴方向上的差异更大,差异有统计学意义(F = 23.141,P < 0.01)。在各个附加度组别中使用 C 字视力表测得视力平均值小于 E 字视力表测得视力平均值,其中斜轴方向的附加组差值更大。C 字视力表在各散光轴位测得视力值差异无统计学意义(F = 1.446,P = 0.231);E 字视力表组在各散光轴位测得视力值相差明显,在斜轴散光中数值与非斜轴散光数值差异有统计学意义。
结论:散光患者使用 C 字视力表更加优异,不同轴向的散光测出来的视力值更加稳定。对于非斜轴散光患者来说,使用 C 字视力表比 E 字视力表更难,用小数记录法记录视力值可能相差 3 ~ 4 行,原因为散光眼在各个方向上的屈光度不一致及 C 字视力表和 E 字视力表的视标形状及排列不同导致。


Objective: To compare the differences of visual acuity measured by C-chart and E-chart under different astigmatism and analyze the reasons for the differences.

Methods: Thirty students aged 15–18 years were selected. Under the condition of fully corrected refractive MPMVA (maximum plus to maximum visual acuity),the corresponding astigmatism was caused by adding corresponding columnar lenses with different astigmatism axes. The corresponding visual acuities measured by two different visual charts. According to the design principle and recording methods of two kinds of visual acuity charts, the possible reasons for the different values are analyzed.
Results: Compared with the E-type visual acuity chart, the average difference of visual acuity measured by adding each axis +0.25 DC columnar lens group was smaller, and the difference between adding +0.50 DC group was larger, especially in the oblique axis direction(F = 23.141,P < 0.01)。The average visual acuity measured by the C-type visual acuity chart in each additional degree group was smaller than that measured by the E-type visual acuity chart, and the difference of the additional group in the oblique axis direction was greater than that measured by the E-type visual acuity chart. There was no significant difference in the visual acuity measured by C-type chart at different astigmatism axes(F = 1.446,P = 0.231);there was a significant difference in the visual acuity values measured by E-type chart at different astigmatism axes, and there was a significant difference in the values of oblique astigmatism and non-oblique astigmatism.
Conclusion: Astigmatism patients with C-type chart obtain more accurate results, and the visual acuity values measured by different axes of astigmatism are more stable. For patients with non-oblique astigmatism, it is more difficult to use C-type chart than E-type chart. The difference of visual acuity recorded by decimal recording method may be 3–4 rows. The reasons are the inconsistency of diopter in different directions of astigmatism and the different shape and arrangement of visual icons between C- and E-type charts.


其他期刊
  • 眼科学报

    主管:中华人民共和国教育部
    主办:中山大学
    承办:中山大学中山眼科中心
    主编:林浩添
    主管:中华人民共和国教育部
    主办:中山大学
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  • Eye Science

    主管:中华人民共和国教育部
    主办:中山大学
    承办:中山大学中山眼科中心
    主编:林浩添
    主管:中华人民共和国教育部
    主办:中山大学
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