Corneal stroma wound healing is a complex process of extracellular matrix (extracellularmatrix,ECM) reconstruction, and the degree of healing is related to corneal transparency. Among them, transforminggrowthfactor--β (TGF- β) signal transduction is the central regulator of matrix healing and fibrosis. Other regulatory factors include myofibroblasts, basement membrane, collagen fibers, small molecular proteoglycans rich in leucine, biophysical signals, proteins from ECM and membrane channels. In this paper, the main regulatory factors and the role of cell phenotype that determine the outcome of matrix healing were reviewed, and a new therapy for reducing matrix opacity was discussed.
The purpose of the eight-year medical education is to train students for well-qualified medical talents that are in line with our national conditions. This article introduces the establishment and development of the eight-year medical education in China, and various aspects of exploration in its reform which includes the reform of the tutoring system, teaching philosophy, teaching approach, means of teaching, special courses and so on. It also summarizes the current situation of the eight-year medical education and discusses potential strategies to improve the education system and the quality of eight-year medical students.
Corona virus disease 2019 (COVID-19) is an acute infectious pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is characterized by respiratory symptoms, but other systems such as digestive system and locomotor system are also frequently involved. There have been some case reports suggesting that patients with COVID-19 may also exhibit ocular symptoms. Based on the latest domestic and foreign literature and related studies, this paper aims to discuss the possibility of eye transmission of SARS-CoV-2, the ocular signs and the possible ocular adverse events after COVID-19 vaccination, and provide references for the prevention and control of ophthalmologists.
Medical students must adhere to the correct political direction because they need to protect people's health in the near future. It is particularly important to integrate ideological education into medical curriculum. Ophthalmic diseases are closely related to systemic diseases. Ophthalmology is a compulsory course of clinical medicine for medical college students. The integration of ideological education into ophthalmology professional courses can encourage students to integrate their personal ideals into national undertaking, motivate students to become strivers and pioneers in the new era. Zhongshan Ophthalmic Center, Sun Yat-sen University taught students according to their aptitude and integrated the ideological contents such as “prevention of blindness” and “myopia prevention” into each chapter of ophthalmology teaching through vivid examples for clinical medical undergraduates. It would be helpful for the students to establish the ideal and values of “serve the people”. At the end of the course, the medical students were investigated by questionnaires to evaluate the effect of ideological education integration, as well as the acceptance and suggestion from the students. The results showed that studentswere satisfied with the teaching quality of ideological contents and the curriculum integration has achieved the desired effect.
Beijing Tongren Hospital has accumulated decades of ophthalmology teaching experience. In recent years, through the application of Problem-Based Learning (PBL) teaching method, we gradually summed up the unique error-distinguished teaching method, which may enhance the understanding of basic knowledge and theories, improve the ability of doctors to discover and solve problems and enhance their independent clinical thinking. At the same time, monthly salon for physician refresher, necessary assessments, various forms of summaries and communication are conducive to promote further learning and produce a good teaching efficiency.
Standardized training for ophthalmology residents is an essential stage during the development of ophthalmologists. The standardized training system has become more and more mature, while problems still exist in the aspects of coordination between specialized hospitals and general hospitals, teacher resources, unevenness of trainees, combination of postgraduate education and residency standardized training, microsurgical skills training, and so on. Therefore, programs and strategies of standardized training are still under exploration. Eye hospitals, with the excellent disciplinary system, adequate resources, and advanced experience, play a key role in standardized training for ophthalmology residents. Joint Shantou International Eye Center has set up a training model in accordance with national requirements, focusing on the combination of standardization, normalization, and individuation. Besides, by learning from the oversea experience of residents training, Joint Shantou International Eye Center has enriched the training forms, optimized the skill training environment, and highlighted the training of foreign language, scientific research, and systematic clinical thinking. This paper, based on the 5-year experience and reflection on standardized training for ophthalmology residents in Joint Shantou International Eye Center, summarizes the current status of standardized training and put forward some measures and suggestions.
The standardized residency training is the essential prerequisite for the training of ophthalmologists in the health system. Based on the emerging problems of standardized residency training in the Department of Ophthalmology in Wuhan Union Hospital, attempts have been made to explore the effectiveness of a comprehensive reform of clinical instruction in areas of content, mode and learning evaluation for residents, as well as incorporating ideological and political elements in the instructional process and faculty training to enhance teaching skills for instructors, which has achieved good results. We hope that the dissemination of such efforts could provoke thoughts on improving the training model for ophthalmological residents and to improve the quality of the ophthalmological training programs in China, and to eventually lead to accumulation of better ophthalmologists in China.
