Peripheral ulcer keratitis (PUK) is a rare but serious ocular condition characterised by progressive crescentic peripheral corneal stromal thinning with associated epithelial defects, which may be associated with underlying local or systemic autoimmune diseases or in an idiopathic form (Mooren's ulcer). Clinically, patients with PUK often present with painful vision loss with PUK. It can be clinically differentiated from marginal keratitis and Terrien's marginal degeneration. Pharmacological treatment is aimed at reducing the local and systemic inflammatory response, and when corneal thinning or perforation occurs, surgical treatment may be indicated in the setting of systemic immunosuppression.

Peripheral ulcer keratitis (PUK) is a rare but serious ocular condition characterised by progressive crescentic peripheral corneal stromal thinning with associated epithelial defects, which may be associated with underlying local or systemic autoimmune diseases or in an idiopathic form (Mooren's ulcer). Clinically, patients with PUK often present with painful vision loss with PUK. It can be clinically differentiated from marginal keratitis and Terrien's marginal degeneration. Pharmacological treatment is aimed at reducing the local and systemic inflammatory response, and when corneal thinning or perforation occurs, surgical treatment may be indicated in the setting of systemic immunosuppression.

Peripheral ulcer keratitis (PUK) is a rare but serious ocular condition characterised by progressive crescentic peripheral corneal stromal thinning with associated epithelial defects, which may be associated with underlying local or systemic autoimmune diseases or in an idiopathic form (Mooren's ulcer). Clinically, patients with PUK often present with painful vision loss with PUK. It can be clinically differentiated from marginal keratitis and Terrien's marginal degeneration. Pharmacological treatment is aimed at reducing the local and systemic inflammatory response, and when corneal thinning or perforation occurs, surgical treatment may be indicated in the setting of systemic immunosuppression.

Peripheral ulcer keratitis (PUK) is a rare but serious ocular condition characterised by progressive crescentic peripheral corneal stromal thinning with associated epithelial defects, which may be associated with underlying local or systemic autoimmune diseases or in an idiopathic form (Mooren's ulcer). Clinically, patients with PUK often present with painful vision loss with PUK. It can be clinically differentiated from marginal keratitis and Terrien's marginal degeneration. Pharmacological treatment is aimed at reducing the local and systemic inflammatory response, and when corneal thinning or perforation occurs, surgical treatment may be indicated in the setting of systemic immunosuppression.

Peripheral ulcer keratitis (PUK) is a rare but serious ocular condition characterised by progressive crescentic peripheral corneal stromal thinning with associated epithelial defects, which may be associated with underlying local or systemic autoimmune diseases or in an idiopathic form (Mooren's ulcer). Clinically, patients with PUK often present with painful vision loss with PUK. It can be clinically differentiated from marginal keratitis and Terrien's marginal degeneration. Pharmacological treatment is aimed at reducing the local and systemic inflammatory response, and when corneal thinning or perforation occurs, surgical treatment may be indicated in the setting of systemic immunosuppression.

Peripheral ulcer keratitis (PUK) is a rare but serious ocular condition characterised by progressive crescentic peripheral corneal stromal thinning with associated epithelial defects, which may be associated with underlying local or systemic autoimmune diseases or in an idiopathic form (Mooren's ulcer). Clinically, patients with PUK often present with painful vision loss with PUK. It can be clinically differentiated from marginal keratitis and Terrien's marginal degeneration. Pharmacological treatment is aimed at reducing the local and systemic inflammatory response, and when corneal thinning or perforation occurs, surgical treatment may be indicated in the setting of systemic immunosuppression.

Peripheral ulcer keratitis (PUK) is a rare but serious ocular condition characterised by progressive crescentic peripheral corneal stromal thinning with associated epithelial defects, which may be associated with underlying local or systemic autoimmune diseases or in an idiopathic form (Mooren's ulcer). Clinically, patients with PUK often present with painful vision loss with PUK. It can be clinically differentiated from marginal keratitis and Terrien's marginal degeneration. Pharmacological treatment is aimed at reducing the local and systemic inflammatory response, and when corneal thinning or perforation occurs, surgical treatment may be indicated in the setting of systemic immunosuppression.

Objective:Explore the Medication Rule and clinical experience of Professor Su Fan in Treating Incommensurate strabismus Based on the ancient and modern medical case cloud platform.Methods:From January 2018 to December 2023, 112 cases were clinically collected, including 244 visits, which were diagnosed as wind-induced bias among ophthalmic inpatients in Yunnan Provincial Hospital of Traditional Chinese Medicine. After data standardization, the gender, age, and age of all cases were analyzed. The distribution of four qi, five flavors and meridian tropism of traditional Chinese medicine were statistically analyzed, and the high-frequency drugs were analyzed by correlation analysis, cluster analysis and complex network analysis, and the frequency and correlation degree of drug combinations, related drug combinations and core prescriptions were obtained, and the results were analyzed, so as to summarize the medication law and clinical experience of Su Fan in treating wind-induced bias.Results:(1)Statistics on the frequency of traditional Chinese medicines: 115 kinds of traditional Chinese medicines were involved in 244 prescriptions, with a total of 2925 times. The top 10 medicines with high frequency of use were: scorpion, centipede, earthworm, Bombyx Batryticatus, Rhizoma Typhonii, Radix Puerariae, Poria, Glycyrrhrizae Radix, Scutellariae Radix and Radix Rehmanniae.(2)Statistics of four qi, five flavors and meridian tropism of traditional Chinese medicine: Statistical results of four qi frequency: four qi are mainly warm. Statistical results of five flavors: pungent, bitter and sweet are the main five flavors. Statistical results of meridian tropism frequency: Meridian tropism is mainly liver, spleen and lung meridians.(3)Correlation statistics of traditional Chinese medicine: take confidence ≥0.5, support ≥0.2 and promotion > 1 to get 26 drug combinations; When the confidence is ≥0.8, the support is ≥0.5, and the promotion is > 1, only a group of centipede-scorpion drug pairs are obtained; Trogopterori-Pollen Typhae, although the support degree is 0.2, the confidence degree is 1, and the promotion degree is 4.78, indicating that this group of drugs is also highly correlated.(4)Cluster statistics of traditional Chinese medicines: after cluster analysis, five drug combinations were obtained: first:Herba Ephedrae, Semen Armeniacae Amarum, Coicis Semen and Scutellariae Radix.Second: Trogopterori, Pollen Typhae, Radix Rehmanniae, Cortex Moutan, Coptidis Rhizoma.Third:Radix Puerariae, Poria, Radix Angelicae Sinensis, Rhizoma Atractylodis, Rhizoma Pinelliae.Fourth:Scorpio, Sco Scolopendra and Lumbricus.Fifth:Rhizoma Typhonii, Bombyx Batryticatus, Herba Asari, Rhizoma Atractylodis Macrocephalae, Rhizoma Chuanxiong, Arisaema cum bile, Radix Glycyrrhizae.(5) Complex network analysis (core formula): Rhizoma Typhonii, Scolopendra, Scorpio, Lumbricus, Bombyx Batryticatus, Poria.Conclusion: Professor Su Fan believed that wind-induced strabismus, although its location is in the eye, is closely related to the liver, spleen, lung, and kidney. Common pathogenic factors include wind, dampness, phlegm, blood stasis, and qi stagnation. In the process of differential diagnosis, one should not be bound by a single method of differential diagnosis and should use various methods of differential diagnosis flexibly. In the process of treatment,"removing wind" should be treatment throughout, and "treating wind" should not forget "treating blood." Su Lao is good at treating wind-induced strabismus with insect drugs, the drug properties are mainly warm, the taste is mainly bitter and sweet, and the meridians are mainly liver, spleen, and lung.

Objective To investigate the effect of the press-and-chop technique in cataract phacoemulsification training. Methods From January 2019 to December 2023, 30 trainees who studied cataract phacoemulsification surgery in the ophthalmology department of Guangdong Hospital of Traditional Chinese Medicine,Zhuhai were selected as the research subjects. The training period for all subjects was 3 months, and they were divided into two groups: phaco-chop teaching group and press-and-chop teaching group. The quantity of porcine eye surgeries performed by each trainee before completing the first nuclear chopping, the quantity of porcine eye surgeries performed before completing all surgical steps for the first time, and the number of times of complete nuclear chopping in one attempt were recorded. At the end of the training, the trainees were assessed on their ability to perform porcine eye surgeries and their scores were recorded. A questionnaire survey was conducted to valuate the two teaching methods. Results The average number of porcine eye surgeries performed by the press-and-chop teaching group before completing the first nuclear chopping was 36.69 (19,50), which was lower than the phaco chop teaching group's 49.86 (29,66);The average number of porcine eye surgeries performed by the press-and-chop teaching group before before the first completion of all surgical steps was 58.13 (31, 79), which was lower than the phaco chop teaching group's 73.14 (50, 90).The average number of complete nuclear chopping in one attempt in the press-and-chop teaching group was 14.75 (9,22), which was higher than the phaco chop teaching group's 6.79 (3,14);The average score of the chopping step of porcine eye surgery for the press-and-chop teaching group was 4.50 (3,5), which was higher than the phaco chop teaching group's 3.71 (2,5);The average score for the press-and-chop teaching group of the complete surgery examination was 29.00 (23, 33), which was higher than the phaco chop teaching group's 23.07 (19, 28).At the end of the training, the average score of the survey questionnaire on the evaluation of teaching effectiveness by the press-and-chop teaching group was 18.31 (15, 20), which was higher than that of the phaco chop, which was 15.07 (12, 18).Conclusions The press-and-chop technique helps trainees to master the chopping technique faster, shorten the learning curve of cataract phacoemulsification surgery, enhance confidence in learning cataract surgery, and improve the teaching effectiveness and satisfaction of cataract phacoemulsification surgery．

Objective To analyze the effects of different cutting ratio SMILE on postoperative dry eye symptoms 、corneal topography and subjective pain. Methods A total of 75 SMILE patients admitted to our hospital from August 2022 to January 2023 were studied. The intraoperative cutting scores were group A (cutting ratio <0.16), group B (cutting ratio 0.16-0.21) and group C (cutting ratio >0.21). Dry eye evaluation included refractive examination results, vision, blink rate, Schirmer Tear Test (SIT), Tear Film Break Up Time, BUT), Ocular Surface Disease Index (OSDI), loss rate of meibomian gland, and Tear Meniscus Height (TMH). The first six items were evaluated before surgery, 1 day after surgery, 10 day after surgery, and 30 day after surgery. The latter two assessments were conducted before surgery and 30 days after surgery. Conduct corneal topographic map examination, select parameters: Surface Asymmetry Index (SAI), Surface Regular Index (SRI) and maximum simulation Kerotoscope Reading (SimuIafed Kerotoscope Reading, SimK), and Numerical Rating Scale (NRS) was used as the pain evaluation index for intraoperative and postoperative pain at different time points. Results The blink frequency of group A was lower than that of group C at 10 and 30 days after surgery, and the difference was statistically significant (P<0.05). At 10d and 30d after surgery, SIT in group C was lower than that in group A; at 1d, 10d and 30d, BUT was lower than that in group A and OSDI score was higher than that in group A; at 30d after surgery, SIT and BUT in group C were lower than that in group B, and OSDI score at each time point was higher than that in group B. There were no differences in the loss rate of meibomian gland and TMH among the three groups (P>0.05). The SAI and SRI of group A were lower than those of group B 10 days after surgery, and the equivalent values of SRI and SimK of group A were higher than those of group B 30 days after surgery. The SAI values of group A and group B at two time points after surgery were lower than those of group C, and the equivalent SimK values were higher than those of group C. SRI of group A was lower than that of group C at 10d and higher than that of group C at 30d (P < 0.05). The intraoperative and 24h postoperative NRS score of group C was significantly higher than that of group A and group B (P<0.05), and the postoperative pain score of each node of the three groups was lower than that of the intraoperative (P<0.05). Conclusion The greater the intraoperative cutting ratio of SMILE, the greater the degree of corneal topographic map change, the higher the postoperative blink rate, and the greater the intraoperative and postoperative NRS pain score.