Central serous chorioretinopathy (CSC) is a common retinal disease caused by multiple factors, and its specific pathogenesis is not fully understood. there is no standard unified treatment plan for CSC, and common treatment options include observation and follow-up, retinal laser therapy, photodynamic therapy (PDT), anti-VEGF drugs, traditional Chinese medicine, and multiple modalities of combined treatment. Subthreshold micropulse laser (SML), as a new retinal laser, has good therapeutic effects on acute and chronic CSC without damaging effects on the retina. In this paper, we will review the mechanism of action and clinical application of subthreshold micropulse laser for the treatment of CSC, and provide some basis for the clinical selection of CSC treatment.