【Abstract】Objective: To analyze the clinical characteristics of retinal arterial macroaneurysm. Design a retrospective case series. The research subjects were 19 patients (19 eyes) with retinal arterial macroaneurysms treated at the Aviation General Hospital and the General Hospital of the People's Liberation Army of China from January 2016 to December 2023. Method: All patients were asked about their medical history and underwent routine eye and fundus examinations (fundus photography,...) OCT, FFA, etc.) inspection. Main indicators: changes in fundus and clinical classification. As a result, the fundus showed only hard exudation in 4 cases (21.1%), bleeding involving subretinal, intraretinal, and retinal areas (3 cases, 15.8%), bleeding involving subretinal and intraretinal areas (3 cases, 15.8%), bleeding involving subretinal and intraretinal areas (3 cases, 15.8%), bleeding involving subretinal and retinal areas (2 cases, 10.5%) with combined hard exudation, only pre retinal bleeding (1 case, 5.3%), and intra retinal bleeding with combined hard exudation (1 case, 5.3%). One case (5.3%) showed gray white atrophic lesions in the tumor body, with a small amount of exudation visible around it (one case, 5.3%). According to the characteristics of fundus photography and fundus fluorescein angiography (FFA), the patients were classified into hemorrhagic type (14 cases, 73.7%), exudative type (4 cases, 21.1%), and stationary type (1 case, 5.3%). Conclusion: The fundus manifestations of retinal arterial macroaneurysm are diverse, with hemorrhagic Retinal arterial macroaneurysm being the most common type.
Objective To explore the current situation of discharge readiness and related factors of patients after glaucoma surgery under the background of DRG payment. Methods A total of 245 patients discharged from glaucoma after surgery were investigated using the General Information Questionnaire, the Discharge Readiness Scale (RHDS), the Discharge Guidance Quality Scale (QDTS) and the Social Support Scale (SSRS). Results The total RHDS score of patients after glaucoma surgery was (90.03±9.28), and the results of regression analysis showed that six variables, including age, education level, length of hospitalization, visual impairment, social support, and quality of discharge guidance, the regression equation is able to explain 71.9% of the total variability. Conclusion Under the background of DRG payment model, the degree of discharge readiness of patients after glaucoma surgery is moderate. Although the quality of discharge guidance is high, there is a certain gap between the depth and breadth of health education content and the actual needs of patients. Therefore, medical staff should further strengthen the assessment of patients' discharge readiness, understand their discharge needs, and provide individualized discharge health education and intervention measures according to age, education level, length of hospitalization, visual impairment, and social support, so as to effectively improve patients' discharge readiness.
[Abstract]: Objective: To investigate the postoperative safety and efficacy of double pedicled conjunctival capsulonostomy. Methods:In retrospective study, 4 cases with 4 eyes of patients with severe lacrimal duct obstruction combined with conjunctival laxity treated in our hospital from september 2023 to March 2024 were selected as the study objects for double-pedicle conjunctival nasal anastomosis surgery. Postoperative follow-up was conducted for 6 months to observe the surgical effect, satisfaction and postoperative complications of the patients Results:1 month after surgery: cured 100%, improved 0%,ineffective 0%; 3 months after surgery: cured 100%, improved 0%, ineffective 0%. 6 months after surgery: 80% cured, 20% improved, 0% ineffective. Conjunctival laxity improved significantly after operation. Conclusion: Compared with the traditional operation, with the single nasal mucosal flap, the length of the nasal mucosal flap increases significantly, which can form the upper anastomotic valve from the nasal cavity to the inner canthus. Compared with the previous surgical methods, this method simplifies the surgical procedure, significantly reduces the difficulty of operation, has a high surgical success rate, fewer complications, is safe and effective, and can improve conjunctival relaxation to a certain extent. It is a very promising surgical method for patients with lacrimal duct obstruction or absence complicated with conjunctival relaxation.
Vitreoretinal lymphoma (Vitreoretinal lymphoma, VRL) is a rare fatal ocular malignancy; the vast majority of VRL is complicated by primary central nervous system lymphoma (primary central nervous system lymphoma, PCNSL), is its special subtype, and a few VRL primary without ocular involvement of the central nervous system and other organs outside the eye are called (Primary vitreoretinal lymphoma, PVRL). VRL lymphoma cells can invade the vitreous, retina, and uvea, leading to diversified clinical manifestations are similar to retinal vasculitis, uveitis, vitritis and other clinical symptoms, clinical symptoms and images are not specific, which is called "camouflage syndrome" is difficult to diagnose.
“锌”在青光眼研究舞台上正扮演着越来越重要的角色。糖皮质激素，作为人体内重要的激素之一，其对锌的调控已在诸多系统中被证实。研究发现，在糖皮质激素的影响下，小梁网中的锌离子转运受阻，导致细胞外基质降解失衡，从而干扰小梁网正常流出道功能，加重青光眼的病情。而视神经损伤后，锌离子在神经突触间的异常传递、不平衡分布与胞内异常累积影响视网膜神经节细胞存活和轴突的再生能力，进而损害视功能，可能成为青光眼视神经损伤发病及进展的关键因素。这些研究进展为视神经保护策略提供了新的视角，“锌”作为治疗靶点的潜力正在被逐步挖掘，通过调节锌水平来干预青光眼病理进程成为可能治疗手段。本期封面中将汉字“锌”设计为飞天舞者，其超越时空的永恒美感，呼应了“锌”在青光眼研究中突破传统、开辟新程的角色。轻盈与自由的飞天舞者，象征着“锌”在细胞内外穿梭，精妙调控生理功能，维系细胞的和谐与平衡，为青光眼患者带来新的治疗希望。
Background: Meningeal carcinomatosis (MC) is a rare complication associated with advanced hematologic and solid tumors. MC may have several ocular manifestations and diagnosis is usually made by magnetic resonance imaging (MRI) and cerebrospinal fluid (CSF) analysis. Most patients with MC require a combination of surgery, chemotherapy, and/or radiation; however, this disease is incurable and the survival rate is extremely low. Case presentation: A 46-year-old woman presented to the ophthalmology department complaining of vision loss. Funduscopy revealed an indistinct margin of the optic disc, along with bilateral papilledema, juxtapapillary exudates, and splinter hemorrhages. A computed tomography (CT) enhanced scan of the chest revealed pulmonary nodules in the apex of the left lung. Lumbar puncture showed the presence of malignant cells in the CSF compatible with a diagnosis of MC. Conclusion: MC is linked to a severe complication of systemic cancer that generally results in poor prognoses. Since ocular symptoms can sometimes be the primary complaint, MC should be suspected in patients with vision loss or diplopia in the absence of an intraocular cause, even without neurologic symptoms and the context of systemic cancer. Systemic examinations of major organs are important for the early discovery, diagnosis, and treatment of MC.
The choroid is a multifunctional, highly vascular, and dynamic tissue which contributes to ocular homeostasis and the regulation of eye growth in both animals and humans. Although challenging to reliably measure, recent advances in ocular imaging (particularly optical coherence tomography) has expanded the current understanding of the role of the choroid in ageing and refractive error development during childhood. This commentary considers recent advances in the field, particularly the impact of orthokeratology on choroidal thickness and contour in myopic children, and the potential use of choroidal metrics as a biomarker for future eye growth.
Aims: To explore the point-wise correlations between 10-2 visual field (VF) metrics and macular vessel density, as measured by optical coherence tomography angiography (OCTA), in patients with primary open-angle glaucoma (POAG) and healthy controls. Methods: This retrospective study included 54 participants (18 POAG patients and 36 healthy controls) from the Zhongshan Ophthalmic Center. All participants underwent comprehensive ophthalmic examinations, 10-2 VF, and macular OCTA imaging. The correlation between capillary density (CD) in macular subregions and light sensitivity (LS) at corresponding VF test points was analyzed using Pearson's correlation coefficients. Results: The analysis revealed a significant reduction in CD within the inferior macular regions of glaucomatous eyes. Notably, there were strong point-wise correlations between CD and 10-2 VF, particularly in the inferior region of outer ring (peak r = 0.534, P < 0.001). Conclusion: Point-wise correlations between 10-2 VF and macular CD suggest potential for using CD to predict VF metrics in glaucoma, highlighting the importance of macular microcirculation in disease assessment.
The widespread application of artificial intelligence (AI) in the medical field has provided new opportunities to explore the relationship between eye and whole body health. This article reviews the application of ophthalmic AI in cardiovascular health, neurological health and aging. In terms of cardiovascular health, AI can predict cardiovascular disease risk factors and future cardiovascular events by analyzing fundus images, and provides a simple and effective risk stratification method. In terms of neurological health, ophthalmic AI shows potential in early diagnosis of Alzheimer's disease and identification of Parkinson's disease, although the prediction of future events remains challenging. For multiple sclerosis, ophthalmic AI has shown good results in diagnosing and predicting the progression of disability. In kidney health, ophthalmic AI technology can predict kidney function-related parameters and detect kidney disease events by analyzing retinal images, demonstrating its potential in improving kidney disease screening methods and reducing medical burdens. In the aging process, AI can use eye images to predict biological age. Parameters such as retinal age gap and LensAge provide biological aging indicators, providing a new perspective for understanding the relationship between aging and eye health.
